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Ulcerative colitis: Diagnosis & Management

Ulcerative colitis is diagnosed through a combination of clinical evaluation, laboratory tests, imaging studies, and endoscopic examination of the colon. Key diagnostic tests include stool studies to rule out infections, blood tests for inflammatory markers like C-reactive protein and fecal calprotectin, and colonoscopy with biopsy to visualize the colon and confirm the diagnosis. Imaging studies like CT scans or MRI may be used to assess disease severity and complications such as toxic megacolon or perforation. Management of ulcerative colitis involves a step-wise approach, starting with anti-inflammatory medications like aminosalicylates for mild to moderate disease.Immunosuppressants such as corticosteroids, thiopurines, or biologics (e.g., anti-TNF agents) are used for moderate to severe disease or if patients do not respond to first-line therapy. Regular monitoring of disease activity through symptom assessment, blood tests, and endoscopic evaluation is crucial for disease management and to prevent complications.

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Dr. Gopi Srikanth

Consultant Gastroenterologist, Yashoda Hospitals, Hyderabad

Dr. Gopi Srikanth, MD (PGIMER), DM & Fellowship (AIIMS, New Delhi), EUS Fellowship (WISE, WEO), is a distinguished gastroenterologist with extensive expertise in digestive and liver diseases, advanced endoscopy, and obesity management. His clinical knowledge and expertise are further strengthened by his distinguished career as a faculty at AIIMS, New Delhi, the most prestigious medical institution in India. He has published several research papers in top medical journals and attended many national conferences as faculty. Currently practicing at Yashoda Hospitals, Hitec City, Dr. Gopi is recognized for his exceptional skills in diagnosing and treating complex gastrointestinal disorders. He is known for his compassionate and patient-centred approach to care and his ability to convey complex medical information in a clear and understandable manner.

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Ulcerative colitis is diagnosed through a combination of clinical evaluation, laboratory tests, imaging studies, and endoscopic examination of the colon. Key diagnostic tests include stool studies to rule out infections, blood tests for inflammatory markers like C-reactive protein and fecal calprotectin, and colonoscopy with biopsy to visualize the colon and confirm the diagnosis. Imaging studies like CT scans or MRI may be used to assess disease severity and complications such as toxic megacolon or perforation. Management of ulcerative colitis involves a step-wise approach, starting with anti-inflammatory medications like aminosalicylates for mild to moderate disease.Immunosuppressants such as corticosteroids, thiopurines, or biologics (e.g., anti-TNF agents) are used for moderate to severe disease or if patients do not respond to first-line therapy. Regular monitoring of disease activity through symptom assessment, blood tests, and endoscopic evaluation is crucial for disease management and to prevent complications.