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Systemic Lupus Erythematosus (SLE)
Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease that can affect various parts of the body, including the skin, joints, kidneys, heart, lungs, brain, and blood vessels. In SLE, the body's immune system mistakenly attacks its own tissues, leading to inflammation and damage. The exact cause of SLE is not fully understood, but it is believed to involve a combination of genetic, environmental, and hormonal factors.One of the hallmark features of SLE is its wide range of symptoms, which can vary greatly from person to person and can also fluctuate over time. Common symptoms include fatigue, joint pain and stiffness, skin rashes (such as the classic "butterfly" rash across the cheeks and nose), fever, photosensitivity (sensitivity to sunlight), hair loss, mouth ulcers, and chest pain with deep breathing.SLE can also cause complications in various organs and systems of the body. For example, inflammation of the kidneys (known as lupus nephritis) can lead to kidney damage and impaired function. Inflammation of the heart and blood vessels can increase the risk of cardiovascular disease. Inflammation of the brain and nervous system can cause headaches, confusion, seizures, and other neurological symptoms.
About the Speaker
Dr. Shanmuganandan Krishnan
Professor SBMCH, Consultant Rheumatology, Apollo Hospitals, Chennai
Brig (Prof.) Krishnan. Shanmuganandan, a distinguished medical professional, brings over 30 years of extensive teaching and clinical experience to the field of medicine. With a robust academic background including an MBBS and MD in Medicine from AFMC, as well as specialized training in Rheumatology, HIV Medicine, and Health Research Methodology, he has continuously contributed to medical education and research. Currently serving as a Professor at SBMCH/BIHER and a Consultant Rheumatologist at prestigious institutions such as Apollo Hospitals and Rela Hospitals in Chennai, Dr. Shanmuganandan excels in clinical problem-solving and diagnosis. His expertise extends to digital health, biosimilar use, immunoinflammatory syndromes, and post-COVID hyperinflammatory immune syndromes. A recipient of commendation medals and awards, he has also been actively involved in editorial roles, MCI assessment, and various professional associations, showcasing his commitment to advancing medical knowledge and healthcare practices in India.
Upcoming Case Discussions
Treatment of Renal Disease in ANCA Vasculitis
The treatment of renal disease in ANCA-associated vasculitis (AAV) typically involves a combination of immunosuppressive therapies to control inflammation and prevent further kidney damage. First-line treatment often includes high-dose corticosteroids and cyclophosphamide or rituximab, both of which help to induce remission by targeting the underlying immune system dysfunction. In cases of kidney failure or rapidly progressive glomerulonephritis, plasmapheresis may be used to remove circulating autoantibodies. Once remission is achieved, maintenance therapy with lower doses of immunosuppressants, such as azathioprine or mycophenolate mofetil, is used to prevent relapses and preserve kidney function.
Management of Pediatric Type 1 Diabetes
Pediatric type 1 diabetes management focuses on maintaining glycemic control while supporting normal growth. Insulin therapy, via multiple daily injections or pumps, is essential, with doses adjusted based on blood glucose monitoring or continuous glucose monitoring (CGM). Nutrition plans emphasizing carbohydrate counting and balanced meals are crucial, alongside adjustments for physical activity to prevent glucose fluctuations. Education for families on recognizing hypo- and hyperglycemia symptoms and managing sick days is vital. Regular follow-ups with a pediatric endocrinologist help monitor HbA1c levels, growth, and complications. Psychosocial support is key for ensuring adherence and addressing emotional challenges.
Rising Cardiac Arrests in Young Entrepreneurs
The increasing cases of cardiac arrests among young entrepreneurs are becoming a serious health concern. Intense stress, long working hours, unhealthy eating habits, and lack of physical activity are major contributors to heart-related issues in this group. This often leads to neglecting personal health, resulting in irregular sleep patterns and chronic fatigue. Additionally, skipping regular medical check-ups can leave underlying heart conditions undetected. Emphasizing stress management, healthy lifestyle choices, and routine health screenings is crucial to reducing this growing risk
Medical Management of Endometriosis
Medical management of endometriosis typically involves the use of hormonal therapies such as birth control pills, progestins, or GnRH agonists to reduce estrogen levels and suppress the growth of endometrial tissue. Pain management with NSAIDs, as well as targeted treatments like aromatase inhibitors or the use of intrauterine devices (IUDs), can help alleviate symptoms. In some cases, additional treatments like surgery may be considered for severe cases or when fertility is a concern.
Analytical Skills in Problem Solving
Today’s session on analytical tools and techniques in healthcare can provide valuable insights into how data-driven approaches enhance decision-making and problem-solving. Sharing personal or professional experiences where analytical skills were effectively used to address challenges can offer practical understanding and inspire learners. These skills are crucial in healthcare for accurate patient diagnosis, effective treatment planning, and efficient resource allocation. By applying analytical methods, healthcare professionals can improve patient outcomes, streamline operations, and make informed, evidence-based decisions that contribute to overall healthcare efficiency and quality.