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Role of Imaging in Neurosciences
Imaging plays a pivotal role in neurosciences by providing non-invasive, detailed insights into the structure and function of the nervous system. Techniques like Magnetic Resonance Imaging (MRI), Functional MRI (fMRI), and Positron Emission Tomography (PET) allow for the visualization of brain anatomy, the mapping of neural activity, and the observation of biochemical processes, respectively. These imaging modalities have revolutionized the understanding of neurological and psychiatric disorders by enabling the identification of structural abnormalities, functional impairments, and neurochemical imbalances. Advanced imaging techniques, such as Diffusion Tensor Imaging (DTI), further facilitate the study of white matter integrity and neural connectivity, offering valuable information about the brain's communication pathways. Imaging is also critical in pre-surgical planning, guiding interventions, and monitoring disease progression or response to treatment. Overall, the integration of various imaging technologies has significantly advanced both research and clinical practice in neurosciences, enhancing diagnostic accuracy, therapeutic strategies, and our fundamental understanding of brain function and dysfunction.
About the Speaker
Dr. Laxminadh Sivaraju
Senior Consultant Neurosurgeon, Care Hospitals, Hyderabad
Dr. Laxminadh Sivaraju is a highly accomplished neurosurgeon currently serving as a Consultant at Continental Hospitals in Hyderabad, India. With an extensive educational background that includes an M.Ch in Neurosurgery from Christian Medical College, Vellore, and an MBBS from Osmania Medical College, Hyderabad, he has demonstrated a steadfast commitment to his profession and patients. His career spans various prestigious institutions where he has gained significant experience in complex neurosurgical procedures, including craniovertebral junction surgeries, epilepsy surgeries, and complex spinal surgeries. Dr. Sivaraju has been recognized with numerous awards, including the Best Paper in Neurosurgery at the 65th Annual Conference of the Neurological Society of India, and has contributed prolifically to peer-reviewed journals, enhancing the field of neurosurgery with his research. He is actively involved in professional societies and has participated in numerous national and international conferences and workshops, further cementing his status as a leading expert in his field.
Upcoming Case Discussions
Treatment of Renal Disease in ANCA Vasculitis
The treatment of renal disease in ANCA-associated vasculitis (AAV) typically involves a combination of immunosuppressive therapies to control inflammation and prevent further kidney damage. First-line treatment often includes high-dose corticosteroids and cyclophosphamide or rituximab, both of which help to induce remission by targeting the underlying immune system dysfunction. In cases of kidney failure or rapidly progressive glomerulonephritis, plasmapheresis may be used to remove circulating autoantibodies. Once remission is achieved, maintenance therapy with lower doses of immunosuppressants, such as azathioprine or mycophenolate mofetil, is used to prevent relapses and preserve kidney function.
Pulmonary Tuberculosis: Challenges in Diagnosis
Diagnosing pulmonary tuberculosis (TB) poses significant challenges, particularly in resource-limited settings. The disease often mimics other respiratory conditions, leading to delayed or missed diagnoses. Traditional diagnostic methods like sputum smear microscopy have limited sensitivity, especially in HIV co-infected or low-bacterial-load patients. Advanced techniques such as GeneXpert and culture tests, though more accurate, are often unavailable in remote areas. Children and immunocompromised patients present additional hurdles due to atypical symptoms and difficulty obtaining diagnostic samples. Non-specific imaging findings further complicate diagnosis. Addressing these challenges requires expanded access to molecular diagnostics, improved point-of-care tools, and greater healthcare awareness.
NIV in Acute Respiratory Failure
Dr Viny Kantroo is a Chest, Critical Care & Sleep medicine specialist based in Delhi, boasting over more than 15 years of professional experience. She is currently practising as a full time Senior consultant in Indraprastha Apollo Hospitals New Delhi and Visiting Consultant Apollo Hospitals Noida in the department of Respiratory, Critical Care and Sleep Medicine. She is recognised for her expertise in various aspects of Chest medicine, which includes EBUS (Convex probe, Radial), Bronchoscopic procedures, pleural effusion management, interstitial lung disease, Covid-19, lung cancer, pneumonia, and intensive care patient management. Dr Kantroo is renowned not only for her medical proficiency but also for her empathy and positive attitude towards patient care. Patients consulting with Dr Viny can be assured of receiving an accurate diagnosis and effective treatment, thanks to her commitment to prompt and comprehensive care.
AI in Genetics and Genomics
AI is revolutionizing genetics and genomics by enabling faster and more accurate analysis of complex genetic data. Machine learning algorithms can identify patterns in DNA sequences, helping to discover new genetic variants linked to diseases. Additionally, AI assists in predicting gene functions, personalizing medicine, and accelerating drug development. Its integration promises significant advancements in understanding genetic diseases and improving healthcare outcomes.
Management of Pediatric Type 1 Diabetes
Pediatric type 1 diabetes management focuses on maintaining glycemic control while supporting normal growth. Insulin therapy, via multiple daily injections or pumps, is essential, with doses adjusted based on blood glucose monitoring or continuous glucose monitoring (CGM). Nutrition plans emphasizing carbohydrate counting and balanced meals are crucial, alongside adjustments for physical activity to prevent glucose fluctuations. Education for families on recognizing hypo- and hyperglycemia symptoms and managing sick days is vital. Regular follow-ups with a pediatric endocrinologist help monitor HbA1c levels, growth, and complications. Psychosocial support is key for ensuring adherence and addressing emotional challenges.