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Systemic Lupus Erythematosus (SLE)
Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease that can affect various parts of the body, including the skin, joints, kidneys, heart, lungs, brain, and blood vessels. In SLE, the body's immune system mistakenly attacks its own tissues, leading to inflammation and damage. The exact cause of SLE is not fully understood, but it is believed to involve a combination of genetic, environmental, and hormonal factors.One of the hallmark features of SLE is its wide range of symptoms, which can vary greatly from person to person and can also fluctuate over time. Common symptoms include fatigue, joint pain and stiffness, skin rashes (such as the classic "butterfly" rash across the cheeks and nose), fever, photosensitivity (sensitivity to sunlight), hair loss, mouth ulcers, and chest pain with deep breathing.SLE can also cause complications in various organs and systems of the body. For example, inflammation of the kidneys (known as lupus nephritis) can lead to kidney damage and impaired function. Inflammation of the heart and blood vessels can increase the risk of cardiovascular disease. Inflammation of the brain and nervous system can cause headaches, confusion, seizures, and other neurological symptoms.
About the Speaker

Dr. Shanmuganandan Krishnan
Professor SBMCH, Consultant Rheumatology, Apollo Hospitals, Chennai
Brig (Prof.) Krishnan. Shanmuganandan, a distinguished medical professional, brings over 30 years of extensive teaching and clinical experience to the field of medicine. With a robust academic background including an MBBS and MD in Medicine from AFMC, as well as specialized training in Rheumatology, HIV Medicine, and Health Research Methodology, he has continuously contributed to medical education and research. Currently serving as a Professor at SBMCH/BIHER and a Consultant Rheumatologist at prestigious institutions such as Apollo Hospitals and Rela Hospitals in Chennai, Dr. Shanmuganandan excels in clinical problem-solving and diagnosis. His expertise extends to digital health, biosimilar use, immunoinflammatory syndromes, and post-COVID hyperinflammatory immune syndromes. A recipient of commendation medals and awards, he has also been actively involved in editorial roles, MCI assessment, and various professional associations, showcasing his commitment to advancing medical knowledge and healthcare practices in India.
Upcoming Case Discussions
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