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Primary Adrenal Insufficiency : A Case Study & Review of Literature
Autoimmune Addison disease affects the function of the adrenal glands, which are small hormone-producing glands located on top of each kidney. It is classified as an autoimmune disorder because it results from a malfunctioning immune system that attacks the adrenal glands. As a result, the production of several hormones is disrupted, which affects many body systems. The signs and symptoms of autoimmune Addison disease can begin at any time, although they most commonly begin between ages 30 and 50. Common features of this condition include extreme tiredness (fatigue), nausea, decreased appetite, and weight loss. In addition, many affected individuals have low blood pressure (hypotension), which can lead to dizziness when standing up quickly; muscle cramps; and a craving for salty foods. A characteristic feature of autoimmune Addison disease is abnormally dark areas of skin (hyperpigmentation), especially in regions that experience a lot of friction, such as the armpits, elbows, knuckles, and palm creases. The lips and the inside lining of the mouth can also be unusually dark. Because of an imbalance of hormones involved in development of sexual characteristics, women with this condition may lose their underarm and pubic hair.
About the Speaker

Dr. Sandip Ghosh
Consultant Endocrinologist, Zulekha Hospitals, Sharjah, UAE
Upcoming Case Discussions
Gynaecologist’s Guide to Ovarian Cancer
Join us for a special webinar on World Ovarian Cancer Day, titled "Gynaecologist’s Guide to Ovarian Cancer." This expert-led session will delve into the latest advancements in early diagnosis, risk stratification, and evidence-based management of ovarian cancer. Tailored for gynecologists and healthcare professionals, the session will also explore real-world case discussions and multidisciplinary treatment approaches. Let’s come together to raise awareness and empower clinicians in the fight against this silent but deadly disease
Massive Transfusion Protocol
Massive Transfusion Protocol (MTP) is a standardized medical procedure activated in cases of severe hemorrhage, typically involving the rapid administration of large volumes of blood products. The goal is to restore circulating volume, maintain hemostasis, and prevent the lethal triad of hypothermia, acidosis, and coagulopathy. MTP usually involves a balanced ratio of packed red blood cells, plasma, and platelets, often in a 1:1:1 ratio. Early activation and coordination among trauma teams, laboratory services, and blood banks are essential for its success.
Clinical Approach In Case of CHD
A congenital heart defect diagnosis can be made either before or after the baby is born. Fetal ultrasonography, which is a common prenatal test, can reveal signs of some cardiac problems. A healthcare provider may suspect a congenital heart abnormality in a newborn if the child has: Growth pauses. Variations in nail, tongue, or lip color. Treatment procedures need to be followed either before or during the diagnosis-making process.
Fever Management in Pediatric Emergency
Fever management in pediatric emergencies involves prompt assessment to determine the underlying cause and severity. Accurate temperature measurement is essential for guiding treatment decisions. Antipyretics like acetaminophen or ibuprofen are commonly used to reduce fever and alleviate discomfort. Monitoring for signs of serious illness, such as meningitis or sepsis, is crucial for timely intervention. Educating caregivers on fever management and when to seek medical help ensures better outcomes for pediatric patients.
Latent Autoimmune Diabetes In Adults
Adult-onset autoimmune disease known as latent autoimmune diabetes of adults (LADA) does not require insulin for glycemic management during the first six months following diagnosis. Although LADA is frequently misdiagnosed as type 2 diabetes, it has genetic, immunologic, and metabolic characteristics with both types 1 and 2 diabetes mellitus (DM) (T2DM). Similar to type 2 diabetes, lifestyle modifications may halt the advancement of LADA, as the condition is caused by multiple unknown variables.