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Non-Variceal Upper GI Bleeding​

The term "non-variceal upper gastrointestinal bleeding" (UVIB) refers to bleeding close to the ligament of Treitz that is not caused by oesophageal, gastric, or duodenal varices. It might be a life-threatening incident, especially in elderly people with comorbidities. Non-variceal UGIB is mostly brought on by peptic ulcer bleeding. The primary risk factors for UGIB include the use of non-steroidal anti-inflammatory medicines, low-dose aspirin usage, and Helicobacter pylori infections. The therapeutic management of NVUGIB is challenging due to the requirement to balance the risk of gastrointestinal bleeding episodes and adverse cardiovascular events in an older population treated with antiplatelet and/or anticoagulant medicines.

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Dr Sushovan Guha Profile Image

Dr Sushovan Guha

Professor Of Medicine, McGovern Medical School Division Of Gastroenterology, Hepatology And Nutrition; Depart Of Internal Medicine Co-Director, Center For Interventional Gastroenterology At UTHealth (IGUT)

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The term "non-variceal upper gastrointestinal bleeding" (UVIB) refers to bleeding close to the ligament of Treitz that is not caused by oesophageal, gastric, or duodenal varices. It might be a life-threatening incident, especially in elderly people with comorbidities. Non-variceal UGIB is mostly brought on by peptic ulcer bleeding. The primary risk factors for UGIB include the use of non-steroidal anti-inflammatory medicines, low-dose aspirin usage, and Helicobacter pylori infections. The therapeutic management of NVUGIB is challenging due to the requirement to balance the risk of gastrointestinal bleeding episodes and adverse cardiovascular events in an older population treated with antiplatelet and/or anticoagulant medicines.