- 77.1k views
Neuroplasticity and its Role on Recovery After Stroke
Neuroplasticity, the brain's remarkable ability to reorganize itself by forming new neural connections, plays a critical role in recovery after stroke. When a stroke occurs, blood flow to parts of the brain is interrupted, causing cell death and impairing function in affected areas. Neuroplasticity facilitates recovery by allowing other parts of the brain to take over the functions lost due to the stroke. This process is driven by the brain's inherent capacity to adapt through mechanisms such as synaptic plasticity, where synapses strengthen or weaken over time, and structural plasticity, involving the growth of new neurons and the reorganization of neural networks. Rehabilitation therapies, such as physical, occupational, and speech therapy, leverage neuroplasticity by providing repetitive, task-specific practice that encourages the brain to rewire itself. Advanced techniques like constraint-induced movement therapy, mirror therapy, and non-invasive brain stimulation further enhance neuroplasticity by promoting activity in the affected regions. The timing and intensity of these interventions are crucial, as the brain is most malleable in the early stages following a stroke. However, neuroplasticity can continue to support recovery even months or years after the initial event. Factors influencing the extent of neuroplastic changes include the severity of the stroke, the individual's age, overall health, and engagement in rehabilitation. Ultimately, neuroplasticity is a foundational concept in stroke recovery, providing a pathway for regaining lost functions and improving quality of life through targeted, adaptive interventions.
About the Speaker

Dr. Dharam P. Pandey
Director & HOD, Department of Physiotherapy & Rehabilitation Sciences, Manipal Hospitals, Delhi
Dr. Dharam P. Pandey, the Director and Head of the Department of Physiotherapy & Rehabilitation Sciences at Manipal Hospitals, Dwarka, Delhi, is a distinguished clinician, researcher, and academic leader with over two decades of experience. His exceptional qualifications include a Ph.D. in Neurological Physiotherapy and advanced certifications from esteemed institutions worldwide in Osteopathy, Neuro-Developmental Treatment, Spinal Structural Balance, and more. Dr. Pandey's pioneering research in AI-powered and frequency-tuned electromagnetic field therapies has significantly advanced non-invasive rehabilitation techniques, earning him recognition in top-tier journals like Frontiers in Neurology and Brain Stimulation. As a dedicated educator, he contributes to academia through roles as a visiting professor, external examiner, and editorial board member. His contributions to neurorehabilitation, particularly in stroke and spinal cord injury recovery, have garnered numerous accolades, including the Best Researcher Award and the Physio Ratan Award. Dr. Pandey's influence extends globally, making him a sought-after speaker at international conferences and a prominent figure in the physiotherapy and rehabilitation sciences community.
Upcoming Case Discussions
Endometriosis and Infertility
Endometriosis is a condition where tissue similar to the lining of the uterus grows outside of it, often affecting the ovaries, fallopian tubes, and pelvic organs. This disorder can cause painful periods, pelvic pain, and, in many cases, infertility. The presence of endometrial-like tissue outside the uterus can disrupt normal reproductive function by causing inflammation, scarring, and adhesions, which can interfere with ovulation, fertilization, and embryo implantation. Approximately 30-50% of women with endometriosis experience infertility, making it one of the leading causes of reproductive challenges in affected individuals. However, treatment options like surgery, medication, or assisted reproductive technologies can help improve fertility outcomes.
Impact of Endometriosis on Fertility
Endometriosis, a condition where endometrial-like tissue grows outside the uterus, can significantly impact fertility. It causes inflammation, scarring, and adhesions that may distort pelvic anatomy, block fallopian tubes, and impair ovarian function. Endometriosis is also linked to hormonal imbalances and poor egg quality, reducing the chances of conception. Symptoms like chronic pelvic pain and painful intercourse further complicate fertility. Diagnosis often requires laparoscopy, while management includes pain relief, hormonal therapy, and assisted reproductive techniques like IVF. Early intervention with medical or surgical treatment can improve reproductive outcomes, but severe cases may necessitate advanced fertility treatments for conception.
Hyperlipidemia: From Diagnosis to Treatment
Hyperlipidemia is a condition characterized by elevated levels of lipids, such as cholesterol and triglycerides, in the blood, which can increase the risk of cardiovascular diseases. Diagnosis typically involves blood tests measuring lipid profiles, while treatment focuses on lifestyle changes, such as diet and exercise, alongside medications like statins to manage cholesterol levels and reduce cardiovascular risk. Regular monitoring is essential for effective management and prevention of complications.
Acne: Disorders and Treatment Approaches
Acne is a common dermatological condition caused by clogged pores, excess sebum production, bacterial growth, and inflammation. It can manifest as blackheads, whiteheads, papules, pustules, or cysts, often leading to scarring if untreated. Various factors, including hormonal changes, diet, stress, and genetics, influence its severity. Treatment approaches range from topical and oral medications, such as retinoids, antibiotics, and hormonal therapy, to advanced procedures like chemical peels and laser therapy. A personalized skincare regimen, along with lifestyle modifications, plays a crucial role in managing and preventing acne.
Abnormal Uterine Bleeding: Diagnosis and Management
Abnormal Uterine Bleeding (AUB) is a common gynecological condition characterized by bleeding outside the normal menstrual cycle, excessive flow, or irregular patterns. It can result from structural causes (polyps, fibroids, adenomyosis, malignancy) or non-structural factors (coagulopathy, ovulatory dysfunction, endometrial disorders). Diagnosis involves a thorough history, physical examination, laboratory tests, imaging (ultrasound), and sometimes hysteroscopy. Management depends on the underlying cause and includes hormonal therapy (oral contraceptives, progestins), non-hormonal options (NSAIDs, tranexamic acid), and surgical interventions (endometrial ablation, myomectomy, hysterectomy). A tailored approach ensures effective symptom control and improved quality of life. Early evaluation is key to preventing complications.