- 42.3k views
Clinician’s Approach to Septic Shock
The prognosis of sepsis syndromes varies and spans a clinical spectrum. The most serious consequence of sepsis, septic shock, has a high death rate. An inciting substance triggers the activation of both the pro-inflammatory and anti-inflammatory immune systems, leading to septic shock. This takes place in tandem with the activation of neutrophils, monocytes, and macrophages, which engage with the endothelium via pathogen recognition receptors and cause further cytokine, protease, kinin, reactive oxygen species, and nitric oxide involvement. The endothelium is the main location of this reaction, and in addition to microvascular damage, it also triggers the complement and coagulation cascades, which worsen the vascular damage and cause capillary leakage. The clinical signs and symptoms of sepsis and the progression from sepsis are caused by this series of events.
About the Speaker
Dr. Ripenmeet Salhotra
Senior Consultant Critical Care, Amrita Hospital, Faridabad
Dr. Ripenmeet Salhotra, Senior Consultant Critical Care, Amrita Hospital, Faridabad
Upcoming Case Discussions
Gynaecologist’s Guide to Ovarian Cancer
Join us for a special webinar on World Ovarian Cancer Day, titled "Gynaecologist’s Guide to Ovarian Cancer." This expert-led session will delve into the latest advancements in early diagnosis, risk stratification, and evidence-based management of ovarian cancer. Tailored for gynecologists and healthcare professionals, the session will also explore real-world case discussions and multidisciplinary treatment approaches. Let’s come together to raise awareness and empower clinicians in the fight against this silent but deadly disease
Massive Transfusion Protocol
Massive Transfusion Protocol (MTP) is a standardized medical procedure activated in cases of severe hemorrhage, typically involving the rapid administration of large volumes of blood products. The goal is to restore circulating volume, maintain hemostasis, and prevent the lethal triad of hypothermia, acidosis, and coagulopathy. MTP usually involves a balanced ratio of packed red blood cells, plasma, and platelets, often in a 1:1:1 ratio. Early activation and coordination among trauma teams, laboratory services, and blood banks are essential for its success.
Sleep Apnea and Daytime Fatigue
Sleep Disorder Breathing is a term for a group of conditions with abnormal breathing patterns during sleep. This affects everyday functioning and well being.There are few types of SDB which include upper airways resistance, hypopnea, apnea, catathrenia and heavy snoring. People suffering with SDB can have daytime symptoms that result in poor sleep also. There can also be sleepiness, depressed mood, irritability and cognitive dysfunction.
Author Post
Impact
+
Talks
+
webinar
+
no.of registrations
One liner about speaker
Why is speaker relevant?
Dr. Ripenmeet Salhotra's Talks on Assimilate
- 08th -Nov -2024, TIME : 4:00PM TO 5:00 PM
- 0
The prognosis of sepsis syndromes varies and spans a clinical spectrum. The most serious consequence of sepsis, septic shock, has a high death rate. An inciting substance triggers the activation of both the pro-inflammatory and anti-inflammatory immune systems, leading to septic shock. This takes place in tandem with the activation of neutrophils, monocytes, and macrophages, which engage with the endothelium via pathogen recognition receptors and cause further cytokine, protease, kinin, reactive oxygen species, and nitric oxide involvement. The endothelium is the main location of this reaction, and in addition to microvascular damage, it also triggers the complement and coagulation cascades, which worsen the vascular damage and cause capillary leakage. The clinical signs and symptoms of sepsis and the progression from sepsis are caused by this series of events.