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Case Discussion on Congenital Hypothyroidism

Congenital hypothyroidism (CH) is a condition in which the thyroid gland is underactive from birth. The thyroid gland produces hormones that regulate metabolism, growth, and development. CH is the most common endocrine disorder in newborns, affecting about 1 in 2,000 to 4,000 births. The condition can lead to intellectual disability and other developmental problems if left untreated.Newborn screening tests can detect CH, and early treatment can prevent complications. CH can be caused by genetic or environmental factors. The most common cause of CH is an underdeveloped or absent thyroid gland. Other causes include defects in the hormone synthesis pathway and maternal thyroid disease. Symptoms of CH may not be apparent at birth but can include poor feeding, constipation, and a hoarse cry. If left untreated, CH can lead to growth failure, intellectual disability, and other developmental delays. Treatment for CH involves lifelong hormone replacement therapy with synthetic thyroid hormone.

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Dr Tejasvi Sheshadrissa

,MD Paediatrics,Consultant Paediatric Endocrinologist, Sparsh Hospitals, Bangalore

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Congenital hypothyroidism (CH) is a condition in which the thyroid gland is underactive from birth. The thyroid gland produces hormones that regulate metabolism, growth, and development. CH is the most common endocrine disorder in newborns, affecting about 1 in 2,000 to 4,000 births. The condition can lead to intellectual disability and other developmental problems if left untreated.Newborn screening tests can detect CH, and early treatment can prevent complications. CH can be caused by genetic or environmental factors. The most common cause of CH is an underdeveloped or absent thyroid gland. Other causes include defects in the hormone synthesis pathway and maternal thyroid disease. Symptoms of CH may not be apparent at birth but can include poor feeding, constipation, and a hoarse cry. If left untreated, CH can lead to growth failure, intellectual disability, and other developmental delays. Treatment for CH involves lifelong hormone replacement therapy with synthetic thyroid hormone.