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Practical use of Insulin : Type 2 Diabetes

A number of landmark randomized clinical trials established that insulin therapy reduces microvascular complications . In addition, recent follow-up data from the U.K. Prospective Diabetes Study (UKPDS) suggests that early insulin treatment also lowers macrovascular risk in type 2 diabetes . Whereas there is consensus on the need for insulin, controversy exists on how to initiate and intensify insulin therapy. The options for the practical implementation of insulin therapy are many. For the management of type 2 diabetes, this resulted in the recommendation to “maintain glycemic levels as close to the nondiabetic range as possible” . However, in contrast to the UKPDS, the Kumamoto study observed a threshold, with no exacerbation of microvascular complications in patients with type 2 diabetes whose A1C was <6.5%, suggesting no additional benefit in lowering A1C below this level

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Dr Anish Behl

MD, DM (Senior Consultant Endocrinologist, Apollo Sugar Clinics, Mysore)

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Dr Anish Behl's Talks on Assimilate

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Dr Anish Behl
  • 28th-October-2022, TIME : 5:30PM - 6:3 0PM
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A number of landmark randomized clinical trials established that insulin therapy reduces microvascular complications . In addition, recent follow-up data from the U.K. Prospective Diabetes Study (UKPDS) suggests that early insulin treatment also lowers macrovascular risk in type 2 diabetes . Whereas there is consensus on the need for insulin, controversy exists on how to initiate and intensify insulin therapy. The options for the practical implementation of insulin therapy are many. For the management of type 2 diabetes, this resulted in the recommendation to “maintain glycemic levels as close to the nondiabetic range as possible” . However, in contrast to the UKPDS, the Kumamoto study observed a threshold, with no exacerbation of microvascular complications in patients with type 2 diabetes whose A1C was <6.5%, suggesting no additional benefit in lowering A1C below this level

webinar
Dr Anish Behl
  • 28th-October-2022, TIME : 5:30PM - 6:3 0PM
  • 0

A number of landmark randomized clinical trials established that insulin therapy reduces microvascular complications . In addition, recent follow-up data from the U.K. Prospective Diabetes Study (UKPDS) suggests that early insulin treatment also lowers macrovascular risk in type 2 diabetes . Whereas there is consensus on the need for insulin, controversy exists on how to initiate and intensify insulin therapy. The options for the practical implementation of insulin therapy are many. For the management of type 2 diabetes, this resulted in the recommendation to “maintain glycemic levels as close to the nondiabetic range as possible” . However, in contrast to the UKPDS, the Kumamoto study observed a threshold, with no exacerbation of microvascular complications in patients with type 2 diabetes whose A1C was <6.5%, suggesting no additional benefit in lowering A1C below this level