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Novel Biomarkers in Sepsis
Elevated levels of PCT serve as a valuable biomarker in sepsis, aiding in the early diagnosis and monitoring of bacterial infections, and guiding therapeutic decisions. CRP is a commonly used biomarker for inflammation, and its levels are frequently elevated in sepsis, providing clinicians with an indication of the severity of the immune response. Elevated lactate levels are associated with tissue hypoxia and serve as a crucial biomarker in sepsis, aiding in the assessment of organ dysfunction and prognosis. Soluble Triggering Receptor Expressed on Myeloid Cells-1 (sTREM-1): Elevated sTREM-1 levels are indicative of bacterial infections, making it a promising biomarker for identifying sepsis of infectious origin. Endothelial Biomarkers (E-selectin, VCAM-1): Increased expression of endothelial biomarkers reflects endothelial dysfunction in sepsis, contributing to the understanding of the pathophysiology and progression of the condition.
About the Speaker
Dr. Adel Mohamed Yasin Al Sisi
Critical care Specialist,Prime Hospitals, Dubai
He has his expertise in critical care and emergency medicine with over 16 years of experience in dealing with acutely ill patients. Additionally he is an international reviewer of ICU articles and Participated as an author in ICU textbooks. He has in interest in Endotracheal and Nasotracheal intubation, use of mechanical ventilation , Insertion of Central Venous and Arterial access , Tapping of pleural effusion- Paracentesis , Pericardiocentesis , use of DC electrical shocks either in Advanced Cardiac Life Support or in the management of tachyarrhythmias.
Upcoming Case Discussions
Endometriosis- Updates
Endometriosis is a chronic gynecological condition where endometrial-like tissue grows outside the uterus, causing pelvic pain, dysmenorrhea, dyspareunia, and infertility. The ectopic tissue responds to hormonal changes, leading to inflammation, adhesions, and scarring. Diagnosis is based on clinical symptoms, imaging (ultrasound, MRI), and confirmed by laparoscopy with biopsy. Treatment includes NSAIDs, hormonal therapy (OCPs, progestins, GnRH analogs), and surgical excision for severe cases. Fertility treatments like IVF may be needed. While not curable, early diagnosis and management can relieve symptoms and improve quality of life.
Case-Based Approach to Managing GI Malignancies
A Case-Based Approach to managing gastrointestinal (GI) malignancies involves applying a personalized, patient-centered strategy using specific case details to guide treatment decisions. It emphasizes a multidisciplinary team approach, where oncologists, surgeons, pathologists, and radiologists collaborate to determine the best course of action based on tumor type, stage, and patient factors. This method allows for tailored treatment plans, integrating surgery, chemotherapy, radiotherapy, and targeted therapies to optimize outcomes. By discussing individual cases, this approach also aids in identifying potential challenges and refining management protocols to improve patient care.
Acne: Disorders and Treatment Approaches
Acne is a common dermatological condition caused by clogged pores, excess sebum production, bacterial growth, and inflammation. It can manifest as blackheads, whiteheads, papules, pustules, or cysts, often leading to scarring if untreated. Various factors, including hormonal changes, diet, stress, and genetics, influence its severity. Treatment approaches range from topical and oral medications, such as retinoids, antibiotics, and hormonal therapy, to advanced procedures like chemical peels and laser therapy. A personalized skincare regimen, along with lifestyle modifications, plays a crucial role in managing and preventing acne.
Cardiac Rehabilitation
Cardiac rehabilitation is a structured program designed to improve cardiovascular health after heart-related conditions such as heart attacks, heart failure, or surgeries like bypass or stenting. It includes supervised exercise, heart-healthy lifestyle education, nutrition counseling, stress management, and medication guidance. The goal is to enhance heart function, reduce the risk of future heart problems, and improve overall well-being. A multidisciplinary team, including doctors, physiotherapists, and dietitians, tailors the program to each patient’s needs. Regular participation in cardiac rehab lowers mortality rates, prevents hospital readmissions, and promotes long-term cardiovascular health, making it an essential part of heart disease recovery.
Role of Telemedicine in Modern Healthcare
Telemedicine plays a crucial role in modern healthcare by enabling remote consultations, reducing the need for in-person visits, and improving access to medical expertise. It enhances patient care through real-time diagnosis, chronic disease management, and mental health support. By integrating AI and digital health technologies, telemedicine streamlines workflows and optimizes healthcare delivery. It is especially beneficial in rural and underserved areas, bridging gaps in specialist care. As technology advances, telemedicine continues to revolutionize healthcare, making it more efficient, accessible, and patient-centered.
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Dr. Adel Mohamed Yasin Al Sisi 's Talks on Assimilate
- 21st-December-2023, TIME : 03:00PM - 04:00PM
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Elevated levels of PCT serve as a valuable biomarker in sepsis, aiding in the early diagnosis and monitoring of bacterial infections, and guiding therapeutic decisions. CRP is a commonly used biomarker for inflammation, and its levels are frequently elevated in sepsis, providing clinicians with an indication of the severity of the immune response. Elevated lactate levels are associated with tissue hypoxia and serve as a crucial biomarker in sepsis, aiding in the assessment of organ dysfunction and prognosis. Soluble Triggering Receptor Expressed on Myeloid Cells-1 (sTREM-1): Elevated sTREM-1 levels are indicative of bacterial infections, making it a promising biomarker for identifying sepsis of infectious origin. Endothelial Biomarkers (E-selectin, VCAM-1): Increased expression of endothelial biomarkers reflects endothelial dysfunction in sepsis, contributing to the understanding of the pathophysiology and progression of the condition.