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Novel Biomarkers in Sepsis
Elevated levels of PCT serve as a valuable biomarker in sepsis, aiding in the early diagnosis and monitoring of bacterial infections, and guiding therapeutic decisions. CRP is a commonly used biomarker for inflammation, and its levels are frequently elevated in sepsis, providing clinicians with an indication of the severity of the immune response. Elevated lactate levels are associated with tissue hypoxia and serve as a crucial biomarker in sepsis, aiding in the assessment of organ dysfunction and prognosis. Soluble Triggering Receptor Expressed on Myeloid Cells-1 (sTREM-1): Elevated sTREM-1 levels are indicative of bacterial infections, making it a promising biomarker for identifying sepsis of infectious origin. Endothelial Biomarkers (E-selectin, VCAM-1): Increased expression of endothelial biomarkers reflects endothelial dysfunction in sepsis, contributing to the understanding of the pathophysiology and progression of the condition.
About the Speaker
Dr. Adel Mohamed Yasin Al Sisi
Critical care Specialist,Prime Hospitals, Dubai
He has his expertise in critical care and emergency medicine with over 16 years of experience in dealing with acutely ill patients. Additionally he is an international reviewer of ICU articles and Participated as an author in ICU textbooks. He has in interest in Endotracheal and Nasotracheal intubation, use of mechanical ventilation , Insertion of Central Venous and Arterial access , Tapping of pleural effusion- Paracentesis , Pericardiocentesis , use of DC electrical shocks either in Advanced Cardiac Life Support or in the management of tachyarrhythmias.
Upcoming Case Discussions
Diabetes and GI Disorders: Understanding the Connection
Dr. Firdous Shaikh is a highly esteemed Consultant Diabetologist and Metabolic Physician based in Mumbai, India, with over six years of experience in diabetes care. Currently, she serves at the Shri Kapol Utkarsh Mandal and Jyoti Clinic, where she has been providing expert consultation since December 2018. Previously, Dr. Shaikh worked as an Associate Consultant Diabetologist at Lina Diabetes Care Centre and held positions at Shetty Nursing Home and Jyoti Polyclinic. She completed his Fellowship in Diabetes and Endocrinology from the Royal College of Physicians in the UK and underwent residency training in Diabetology at the Asian Heart Institute. Dr. Shaikh is dedicated to advancing diabetes management and improving patient outcomes through personalized care and ongoing education.
CAR T Cells in Cancer Gene Therapy
CAR T-cell therapy is a groundbreaking approach in cancer gene therapy that harnesses a patient’s immune cells to target and destroy cancer cells. In this technique, T-cells are genetically modified to express chimeric antigen receptors (CARs) that specifically recognize cancer cells. Once reintroduced into the patient, these CAR T-cells seek out and eliminate cancer cells with high precision. This therapy has shown remarkable success in treating certain types of blood cancers, such as leukemia and lymphoma, and is being explored for solid tumors. CAR T-cell therapy offers a promising personalized treatment, with ongoing research aimed at enhancing its safety, effectiveness, and applicability to a wider range of cancers.
Pediatric Epilepsy: Diagnosis and Long-term Management
Pediatric epilepsy is a neurological disorder marked by recurrent seizures, affecting around 1% of children worldwide. Early and accurate diagnosis is crucial for effective management, involving a thorough clinical history, physical exams, EEG, and imaging studies like MRI. Identifying seizure type and underlying causes—such as genetic, structural, or metabolic factors—guides treatment strategies. Long-term management typically includes antiepileptic medications tailored to seizure type and child response, with regular monitoring for side effects and efficacy. For medication-resistant cases, additional treatments like dietary therapy (e.g., ketogenic diet), vagus nerve stimulation, or surgery may be explored. Beyond seizure control, managing comorbidities such as cognitive delays, behavioral issues, and psychosocial challenges is essential for holistic care. Collaborating closely with healthcare providers, caregivers play a key role in monitoring, ensuring adherence, and supporting the child’s quality of life, education, and social integration.
Latest Surgical Approaches to Oral Cancer
Recent advancements in surgical approaches to oral cancer have emphasized precision and minimally invasive techniques. Robotic-assisted surgery and transoral laser microsurgery allow for enhanced accuracy, reducing damage to surrounding tissues. Surgeons also increasingly use image-guided technology, which enhances visualization and helps remove tumors more effectively. Sentinel lymph node biopsy has become a standard for early-stage oral cancer, enabling better staging with minimal invasiveness. These advancements contribute to faster recovery times, reduced complications, and improved overall outcomes for patients.
Urinary Tract Infections: Clinical Approach and Management
An infection of the urinary system is known as a urinary tract infection (UTI). The urethra (urethritis) may be affected by this kind of infection (pyelonephritis) kidneys, bladder (cystitis). A consequence of kidneys' blood-filtering function is urine, or pee. When waste materials and extra water are eliminated from your circulation, your kidneys produce urine. Normally, urine passes through your urinary system uncontaminated. However, UTIs can result from bacteria entering the urinary system.
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Dr. Adel Mohamed Yasin Al Sisi 's Talks on Assimilate
- 21st-December-2023, TIME : 03:00PM - 04:00PM
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Elevated levels of PCT serve as a valuable biomarker in sepsis, aiding in the early diagnosis and monitoring of bacterial infections, and guiding therapeutic decisions. CRP is a commonly used biomarker for inflammation, and its levels are frequently elevated in sepsis, providing clinicians with an indication of the severity of the immune response. Elevated lactate levels are associated with tissue hypoxia and serve as a crucial biomarker in sepsis, aiding in the assessment of organ dysfunction and prognosis. Soluble Triggering Receptor Expressed on Myeloid Cells-1 (sTREM-1): Elevated sTREM-1 levels are indicative of bacterial infections, making it a promising biomarker for identifying sepsis of infectious origin. Endothelial Biomarkers (E-selectin, VCAM-1): Increased expression of endothelial biomarkers reflects endothelial dysfunction in sepsis, contributing to the understanding of the pathophysiology and progression of the condition.