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Management of Neuropathic Pain
Diabetic polyneuropathy is a common complication of diabetes mellitus, characterized by nerve damage throughout the body due to prolonged high blood sugar levels. Symptoms can vary widely, including numbness, tingling, burning pain, weakness, and loss of sensation, typically starting in the feet and gradually spreading to other areas. Diagnosis involves a thorough medical history, neurological examination, and nerve conduction studies. Management focuses on glycemic control through medications, lifestyle modifications, and pain management strategies such as analgesics, anticonvulsants, and antidepressants. Additionally, addressing risk factors such as smoking, hypertension, and dyslipidemia is crucial. Regular monitoring for complications such as foot ulcers and autonomic dysfunction is essential for preventing further nerve damage and improving quality of life.
About the Speaker

Dr. Usama Hassan Saleh
Consultant Orthopedic Surgeon, Medcare Hospitals, Dubai
Dr. Usama Hassan Saleh is currently working as Consultant Orthopedic Surgeon at Medcare Hospitals, Dubai. He earned his medical degree in Egypt before pursuing a clinical fellowship in upper extremity surgery at the University of Toronto, Canada. Holding membership in The Royal College of Surgeons of England (MRCS UK), he furthered his expertise by completing a PhD thesis in knee surgery at Cairo University. Dr. Hassan specializes in sports injuries and arthroscopic surgery of the shoulder, knee, elbow, and wrist, with additional focus on joint replacement surgery of the knee, shoulder, and hip. With extensive training in trauma surgery, including advanced training at the University of Toronto Hospitals, he actively contributes to teaching trauma surgery to junior orthopedic surgeons in the region as an International AO Trauma Faculty.
Upcoming Case Discussions
Chest Pain: Cardiac vs Non-Cardiac Causes
Chest pain can arise from both cardiac and non-cardiac causes, making accurate diagnosis crucial. Cardiac-related chest pain is often linked to conditions like angina or heart attacks, typically presenting as pressure or tightness in the chest. Non-cardiac causes may include musculoskeletal issues, acid reflux, or anxiety, often characterized by sharp or localized pain. Symptoms such as pain radiating to the arm, jaw, or shortness of breath may indicate a cardiac origin. A thorough medical evaluation, including ECG and imaging, is essential to determine the underlying cause and ensure appropriate treatment.
Hyperlipidemia: From Diagnosis to Treatment
Hyperlipidemia is a condition characterized by elevated levels of lipids, such as cholesterol and triglycerides, in the blood, which can increase the risk of cardiovascular diseases. Diagnosis typically involves blood tests measuring lipid profiles, while treatment focuses on lifestyle changes, such as diet and exercise, alongside medications like statins to manage cholesterol levels and reduce cardiovascular risk. Regular monitoring is essential for effective management and prevention of complications.
Role of GLP 1 RA in Weight loss
GLP-1 receptor agonists (GLP-1 RAs) play a significant role in weight loss by enhancing insulin secretion, inhibiting glucagon release, and slowing gastric emptying, which helps reduce appetite and food intake. These medications, originally developed for managing type 2 diabetes, have been shown to promote substantial weight loss in overweight and obese individuals, even in the absence of diabetes. GLP-1 RAs, such as liraglutide and semaglutide, have been approved for weight management and are often used alongside lifestyle interventions. Their effectiveness in weight loss, combined with improved metabolic control, makes them a promising treatment option for individuals struggling with obesity.
Alpha Lipoic Acid: Pharmacokinetics & Applications
Alpha-lipoic acid (ALA) is a naturally occurring antioxidant involved in mitochondrial energy metabolism. It is rapidly absorbed in the gastrointestinal tract and distributed throughout the body, with high concentrations in the liver and kidneys. ALA is both water- and fat-soluble, allowing it to neutralize free radicals in various environments. It undergoes extensive hepatic metabolism and is excreted primarily via the urine. ALA has therapeutic applications in managing conditions like diabetes, neurodegenerative diseases, and as a supplement for its antioxidant benefits.
Acne: Disorders and Treatment Approaches
Acne is a common dermatological condition caused by clogged pores, excess sebum production, bacterial growth, and inflammation. It can manifest as blackheads, whiteheads, papules, pustules, or cysts, often leading to scarring if untreated. Various factors, including hormonal changes, diet, stress, and genetics, influence its severity. Treatment approaches range from topical and oral medications, such as retinoids, antibiotics, and hormonal therapy, to advanced procedures like chemical peels and laser therapy. A personalized skincare regimen, along with lifestyle modifications, plays a crucial role in managing and preventing acne.