Description
Insulin dysregulation disrupts the body's ability to regulate blood sugar, leading to metabolic disorders like diabetes, obesity, and insulin resistance. Excess insulin production (hyperinsulinemia) can cause weight gain, inflammation, and hormonal imbalances. On the other hand, insulin resistance forces the pancreas to overwork, increasing the risk of type 2 diabetes. Poor diet, stress, and sedentary lifestyles contribute to this dysfunction. Managing insulin levels through balanced nutrition, regular exercise, and stress reduction is crucial for metabolic health. Early intervention can prevent long-term complications like cardiovascular disease and organ damage.
Summary Listen
- Insulin dysregulation is conventionally viewed as the primary driver of metabolic dysfunction, leading to hyperinsulinemia, insulin resistance, and subsequent diseases. This conventional perspective suggests that excessive carbohydrate intake, stress, and endocrine disruptors cause elevated insulin levels, receptor downregulation, and impaired sugar utilization, culminating in fat accumulation, inflammation, and mitochondrial dysfunction.
- However, the presentation challenges this conventional view by asserting that metabolic dysfunction, specifically poor mitochondrial health, precedes and contributes to insulin resistance. When mitochondria become compromised in quality, number, and size, cellular energy production becomes inefficient, leading to reduced glucose and fat burning, ultimately resulting in insulin resistance and elevated insulin levels.
- Mitochondria plays a vital role in various bodily processes, including metabolic regulation, cell death control, energy production, epigenetics, inflammation, hormone synthesis, and environmental sensing. Dysfunction in these processes can lead to diabetes, cardiovascular diseases, renal problems, neurodegeneration, and aging.
- Early detection of metabolic dysfunction can be achieved by assessing mitochondrial function through organic acid tests, specifically monitoring lactate and pyruvate levels. Fasting insulin levels can also serve as an early indicator, with optimal levels around 5-6, while elevated levels may suggest insulin resistance.
- Damage to mitochondria can be caused by various factors, including insufficient nourishment, toxin overload, inflammation, oxidative stress, nutrient deficiencies, lack of exercise, blue light toxicity, chronic stress, infections, dehydration, sleep deprivation, electromagnetic fields, and antibiotic overuse.
- Strategies for improving mitochondrial health include optimizing circadian biology, nourishing the body with adequate fats, proteins, minerals, and vitamins, maintaining hydration, improving gut microbiome health, and detoxifying the body. Additional interventions, such as photobiomodulation, deuterium-depleted water, ozone therapy, exosomes, and peptide therapies, can further enhance mitochondrial function.
Sample Certificate
About the Speakers
Dr. Ashwani Garg
Consultant Chronic Disease Reversal & Brain Health, Functional Medicine Clinic, Bengaluru
Financial Disclosure
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