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Hypertension: mechanism and approach to target organ protection
Hypertension is a common condition characterized by abnormally high blood pressure levels. The mechanism underlying hypertension involves an increase in peripheral vascular resistance and/or an increase in cardiac output. Several factors can contribute to the development of hypertension, including age, family history, obesity, physical inactivity, and smoking. Hypertension can cause damage to target organs such as the heart, kidneys, and brain, leading to cardiovascular disease, renal failure, and stroke. Effective management of hypertension involves targeting the underlying mechanism and implementing measures to protect target organs from damage. The mainstay of hypertension management is lifestyle modifications, including weight loss, regular physical activity, and a healthy diet. In addition to lifestyle modifications, pharmacological interventions are also used to manage hypertension. Antihypertensive medications can be classified based on their mechanism of action, including diuretics, beta-blockers, calcium channel blockers, and angiotensin-converting enzyme (ACE) inhibitors.
About the Speaker

Dr.Ramkumar Sundaraperumal
HOD and Specialist Internal Medicine, Zulekha hospital, Dubai
Upcoming Case Discussions
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Join us for a special webinar on World Ovarian Cancer Day, titled "Gynaecologist’s Guide to Ovarian Cancer." This expert-led session will delve into the latest advancements in early diagnosis, risk stratification, and evidence-based management of ovarian cancer. Tailored for gynecologists and healthcare professionals, the session will also explore real-world case discussions and multidisciplinary treatment approaches. Let’s come together to raise awareness and empower clinicians in the fight against this silent but deadly disease
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Massive Transfusion Protocol (MTP) is a standardized medical procedure activated in cases of severe hemorrhage, typically involving the rapid administration of large volumes of blood products. The goal is to restore circulating volume, maintain hemostasis, and prevent the lethal triad of hypothermia, acidosis, and coagulopathy. MTP usually involves a balanced ratio of packed red blood cells, plasma, and platelets, often in a 1:1:1 ratio. Early activation and coordination among trauma teams, laboratory services, and blood banks are essential for its success.
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