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Gestational Diabetes Mellitus
Gestational Diabetes Mellitus (GDM) is a condition characterized by elevated blood sugar levels during pregnancy, typically developing in the second or third trimester. It arises when the body cannot produce enough insulin to meet the increased demands of pregnancy, leading to insulin resistance. GDM poses risks to both the mother and the baby, including preeclampsia, preterm birth, and higher birth weight, which can complicate delivery. Mothers with GDM are also at increased risk for developing type 2 diabetes later in life. Management includes lifestyle modifications, such as diet and exercise, and, in some cases, medication to maintain blood glucose levels within a target range.
About the Speaker
![Dr. Dina Nagodra Mithani Profile Image](https://assimilate.one/wp-content/uploads/2024/06/Dr.-Dina-Nagodra-Mithani.png)
Dr. Dina Nagodra Mithani
Endocrinologist, DENMARC Institute, Mumbai
Dr. Dina Nagodra Mithani is a highly qualified and experienced diabetes and endocrinology specialist with a comprehensive educational background and extensive international work experience. She holds postgraduate diplomas in endocrinology and diabetes from the University of South Wales, the International Diabetes Federation, the Royal College of Physicians, and Fortis CDOC, as well as a postgraduate certificate in stem cell and regenerative medicine from the University of Utrecht. Additionally, she has a Master of Science in Public and Tropical Health and was promoted for a PhD at the University of Medical Sciences and Technology in Sudan, where she also earned her Bachelor of Science in Medicine and Surgery. Dr. Mithani's career spans several countries, including roles at the DENMARC Institute in Mumbai, the Omdurman Military Hospital in Sudan, the Norfolk and Norwich University Hospital in the UK, and the Midland Regional Hospital in Ireland. She has provided diabetes and endocrinology services in various clinical settings, such as the Acute Medical Assessment Unit at Wexford General Hospital and the Abdalla Khalil Diabetes Center in Sudan. Her experience also includes working in intensive care at Imperial Private Hospital and serving with the State Ministry of Health in Khartoum. In addition to her clinical work, Dr. Mithani has contributed significantly to medical research, with publications in esteemed journals like the New England Journal of Medicine. Her research topics include diabetes in pregnancy, the relationship between diabetes and heart failure, diabetic neuropathy, cardiometabolic disease, and novel therapies for diabetes management. Dr. Mithani's dedication to her field is reflected in her ongoing efforts to improve diabetes care and outcomes for patients globally.
Upcoming Case Discussions
Clinician’s Approach to Hypertensive Nephropathy
Many processes influence the management of chronic kidney disease (CKD) and lead to the development of hypertension in the disease. Increased sympathetic tone in patients with chronic kidney disease (CKD) is a result of afferent signals produced by functionally failing kidneys. The great majority of CKD patients suffer from hypertension, which can both cause and result from the disease. In people with CKD, controlling hypertension is crucial since it lowers the risk of CVD and slows the disease's course. There is no agreement on the ideal blood pressure (BP) targets provided by current guidelines. Consequently, when deciding how to care specific patients.
Anaphylaxis In Emergency Department
A dangerous systemic hypersensitivity reaction with a typically quick onset that can be fatal is anaphylaxis. Rapid onset of breathing, circulation,and/or airway issues are its defining characteristics. The most crucial treatment is intramuscular adrenaline, although many patients do not receive it even in medical facilities, despite recommendations to the contrary. The significance of positioning during the management of anaphylaxis and the necessity of avoiding activities that could postpone the timely and proper delivery of adrenaline. Antihistamines should only be used as a last resort when ABC characteristics have been successfully treated in order to lessen skin involvement.
Circulatory Shock In Trauma
The inability of the circulatory system to supply tissue oxygenation and organ perfusion necessary to meet cellular metabolic demands is known as shock. Although non-haemorrhagic shock, such as cardiogenic or neurogenic shock, can occur after trauma, hemorrhage is more frequently linked to trauma-related shock. Evidence gathered over the past ten years has shown that trauma patients suffer from acute traumatic coagulopathy (ATC), which is brought on by the actual process of injury. Damage control resuscitation (DCR), the current method for managing acute shock, was developed with this as a key component. Haemostatic resuscitation, which uses blood products as the main resuscitative fluid, permissive hypotension, and damage control surgery are the three main resuscitative techniques included in DCR.
Fertilization & Early Development
Fertilization occurs when a sperm cell merges with an egg cell, creating a zygote, which is the first stage of a new life. This process takes place in the fallopian tube. The zygote then undergoes rapid cell division, known as cleavage, forming a multi-cellular structure called a blastocyst. As the blastocyst moves toward the uterus, it continues to divide and develop. Approximately 5-7 days after fertilization, the blastocyst implants itself into the uterine lining, initiating pregnancy. Early development involves the formation of the foundational structures and systems that will shape the embryo.
Normalizing Conversations on Mental Health
Normalizing conversations about mental health is essential to breaking the stigma that surrounds mental illness. Open discussions encourage individuals to seek help without fear of judgment, making mental health care more accessible. By talking about mental health as we do physical health, we create a supportive environment where people feel understood and accepted. Education and awareness play crucial roles in changing perceptions and promoting empathy. When mental health becomes a regular part of our conversations, it fosters early intervention and better coping strategies. This cultural shift can lead to improved overall well-being and a reduction in mental health crises.