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Combatting TB: Prevention and Treatment Essentials
Combatting tuberculosis (TB) requires a multifaceted approach that includes both prevention and treatment strategies to effectively control the spread of the disease. Prevention efforts focus on identifying and treating latent TB infection, as well as implementing measures to reduce transmission in high-risk populations. Vaccination with the Bacillus Calmette-Guérin (BCG) vaccine in childhood is a key preventive measure, although its efficacy varies in different populations. Screening for TB infection through tuberculin skin tests or interferon-gamma release assays helps identify individuals at risk of developing active TB. Treatment of active TB involves a combination of antibiotics for an extended period, typically six to nine months, to ensure complete eradication of the bacteria. Directly Observed Therapy (DOT) programs help ensure medication adherence and reduce the risk of drug resistance. Drug-resistant TB strains pose a significant challenge, requiring specialized treatment regimens with second-line antibiotics and close monitoring.
About the Speaker
Dr. Padmanesan Narasimhan
Digital Health Roster of Experts at World Health Organization, Lecturer School of Public Health & Community Medicine, UNSW, Australia.
Dr. Padma Narasimhan is a Clinician and Lecturer at the School of Public Health. He started his career as a medical doctor in India for an Infectious disease clinic. He completed the Fogarty Ellison Clinical Research Fellowship at National Institutes of Health, USA in 2006 and moved to Australia . Dr. Padma Narasimhan was awarded the UNSW-University International Postgraduate Scholarship for a PhD at the School.
Upcoming Case Discussions
Chest Pain: Cardiac vs Non-Cardiac Causes
Chest pain can arise from both cardiac and non-cardiac causes, making accurate diagnosis crucial. Cardiac-related chest pain is often linked to conditions like angina or heart attacks, typically presenting as pressure or tightness in the chest. Non-cardiac causes may include musculoskeletal issues, acid reflux, or anxiety, often characterized by sharp or localized pain. Symptoms such as pain radiating to the arm, jaw, or shortness of breath may indicate a cardiac origin. A thorough medical evaluation, including ECG and imaging, is essential to determine the underlying cause and ensure appropriate treatment.
Hyperlipidemia: From Diagnosis to Treatment
Hyperlipidemia is a condition characterized by elevated levels of lipids, such as cholesterol and triglycerides, in the blood, which can increase the risk of cardiovascular diseases. Diagnosis typically involves blood tests measuring lipid profiles, while treatment focuses on lifestyle changes, such as diet and exercise, alongside medications like statins to manage cholesterol levels and reduce cardiovascular risk. Regular monitoring is essential for effective management and prevention of complications.
Role of GLP 1 RA in Weight loss
GLP-1 receptor agonists (GLP-1 RAs) play a significant role in weight loss by enhancing insulin secretion, inhibiting glucagon release, and slowing gastric emptying, which helps reduce appetite and food intake. These medications, originally developed for managing type 2 diabetes, have been shown to promote substantial weight loss in overweight and obese individuals, even in the absence of diabetes. GLP-1 RAs, such as liraglutide and semaglutide, have been approved for weight management and are often used alongside lifestyle interventions. Their effectiveness in weight loss, combined with improved metabolic control, makes them a promising treatment option for individuals struggling with obesity.
Alpha Lipoic Acid: Pharmacokinetics & Applications
Alpha-lipoic acid (ALA) is a naturally occurring antioxidant involved in mitochondrial energy metabolism. It is rapidly absorbed in the gastrointestinal tract and distributed throughout the body, with high concentrations in the liver and kidneys. ALA is both water- and fat-soluble, allowing it to neutralize free radicals in various environments. It undergoes extensive hepatic metabolism and is excreted primarily via the urine. ALA has therapeutic applications in managing conditions like diabetes, neurodegenerative diseases, and as a supplement for its antioxidant benefits.
Acne: Disorders and Treatment Approaches
Acne is a common dermatological condition caused by clogged pores, excess sebum production, bacterial growth, and inflammation. It can manifest as blackheads, whiteheads, papules, pustules, or cysts, often leading to scarring if untreated. Various factors, including hormonal changes, diet, stress, and genetics, influence its severity. Treatment approaches range from topical and oral medications, such as retinoids, antibiotics, and hormonal therapy, to advanced procedures like chemical peels and laser therapy. A personalized skincare regimen, along with lifestyle modifications, plays a crucial role in managing and preventing acne.
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Dr. Padmanesan Narasimhan's Talks on Assimilate
- 22nd-March-2024, TIME : 4:00PM - 5:00PM
- 0
Combatting tuberculosis (TB) requires a multifaceted approach that includes both prevention and treatment strategies to effectively control the spread of the disease. Prevention efforts focus on identifying and treating latent TB infection, as well as implementing measures to reduce transmission in high-risk populations. Vaccination with the Bacillus Calmette-Guérin (BCG) vaccine in childhood is a key preventive measure, although its efficacy varies in different populations. Screening for TB infection through tuberculin skin tests or interferon-gamma release assays helps identify individuals at risk of developing active TB. Treatment of active TB involves a combination of antibiotics for an extended period, typically six to nine months, to ensure complete eradication of the bacteria. Directly Observed Therapy (DOT) programs help ensure medication adherence and reduce the risk of drug resistance. Drug-resistant TB strains pose a significant challenge, requiring specialized treatment regimens with second-line antibiotics and close monitoring.
- 22nd-March-2024, TIME : 4:00PM - 5:00PM
- 0
Combatting tuberculosis (TB) requires a multifaceted approach that includes both prevention and treatment strategies to effectively control the spread of the disease. Prevention efforts focus on identifying and treating latent TB infection, as well as implementing measures to reduce transmission in high-risk populations. Vaccination with the Bacillus Calmette-Guérin (BCG) vaccine in childhood is a key preventive measure, although its efficacy varies in different populations. Screening for TB infection through tuberculin skin tests or interferon-gamma release assays helps identify individuals at risk of developing active TB. Treatment of active TB involves a combination of antibiotics for an extended period, typically six to nine months, to ensure complete eradication of the bacteria. Directly Observed Therapy (DOT) programs help ensure medication adherence and reduce the risk of drug resistance. Drug-resistant TB strains pose a significant challenge, requiring specialized treatment regimens with second-line antibiotics and close monitoring.