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Case Discussion on Abnormal Uterine Bleeding in Pre & Post Menopausal Women
Abnormal uterine bleeding (AUB) is a significant concern that can affect women in both premenopausal and postmenopausal stages. In premenopausal women, AUB may manifest as irregular or heavy menstrual bleeding, often due to hormonal imbalances, uterine fibroids, or polyps. The evaluation typically involves a thorough history, physical examination, and sometimes imaging or endometrial biopsy to identify the underlying cause. In postmenopausal women, any vaginal bleeding after 12 months of amenorrhea is considered abnormal and requires immediate evaluation to rule out endometrial cancer or other serious conditions. Transvaginal ultrasound and endometrial sampling are essential diagnostic tools in this population. Management strategies vary depending on the cause, and may include medical treatments, hormonal therapies, hysteroscopic procedures, or, in severe cases, hysterectomy.
About the Speaker

DR JASMIN RATH
Gynecologist and laproscopy surgeon in apollo hospital hyderabad
Upcoming Case Discussions
Alpha Lipoic Acid: Pharmacokinetics & Applications
Alpha-lipoic acid (ALA) is a naturally occurring antioxidant involved in mitochondrial energy metabolism. It is rapidly absorbed in the gastrointestinal tract and distributed throughout the body, with high concentrations in the liver and kidneys. ALA is both water- and fat-soluble, allowing it to neutralize free radicals in various environments. It undergoes extensive hepatic metabolism and is excreted primarily via the urine. ALA has therapeutic applications in managing conditions like diabetes, neurodegenerative diseases, and as a supplement for its antioxidant benefits.
Acne: Disorders and Treatment Approaches
Acne is a common dermatological condition caused by clogged pores, excess sebum production, bacterial growth, and inflammation. It can manifest as blackheads, whiteheads, papules, pustules, or cysts, often leading to scarring if untreated. Various factors, including hormonal changes, diet, stress, and genetics, influence its severity. Treatment approaches range from topical and oral medications, such as retinoids, antibiotics, and hormonal therapy, to advanced procedures like chemical peels and laser therapy. A personalized skincare regimen, along with lifestyle modifications, plays a crucial role in managing and preventing acne.
Severe Obesity in a Young Adult: Correct Approach
Severe obesity in young adults requires a comprehensive, multidisciplinary approach that addresses both the physical and psychological aspects of the condition. The first step is a thorough medical evaluation, including assessments of underlying causes, comorbidities, and the impact of obesity on overall health. A combination of evidence-based interventions such as lifestyle changes (diet and exercise), behavioral therapy, and, in some cases, pharmacotherapy or bariatric surgery may be necessary for effective management. It's crucial for healthcare providers to offer ongoing support, emphasizing a non-judgmental, patient-centered approach to ensure long-term success and improved quality of life.
Clinician’s Approach to Bronchiectasis
A clinician's approach to bronchiectasis begins with a thorough patient history and physical examination to identify symptoms such as chronic cough, sputum production, and recurrent respiratory infections. Diagnostic imaging, particularly high-resolution CT scans, is essential for confirming the presence and extent of bronchial damage. Treatment typically involves addressing the underlying cause (e.g., infections, autoimmune diseases), managing symptoms with bronchodilators, airway clearance techniques, and antibiotics, as needed. Long-term management may also include pulmonary rehabilitation, immunizations, and close monitoring to prevent exacerbations and preserve lung function.
Fluid Management: Crystalloids Vs Colloids
Crystalloids and colloids are essential for fluid resuscitation, each with distinct properties. Crystalloids (e.g., normal saline, Ringer’s lactate) are inexpensive, readily available, and primarily restore intravascular volume through redistribution in the extracellular space. They require larger volumes for effective resuscitation but have fewer complications. Colloids (e.g., albumin, hydroxyethyl starch) contain larger molecules, maintaining oncotic pressure and staying longer in circulation. They require smaller volumes but are costlier and may pose risks like coagulopathy or kidney injury. The choice depends on clinical context, with crystalloids being first-line in most scenarios due to safety and efficacy.