The coexistence of Chronic Obstructive Pulmonary Disease (COPD) and Obstructive Sleep Apnea (OSA), known as overlap syndrome, significantly increases morbidity and mortality. Clinicians should suspect overlap in COPD patients with persistent daytime sleepiness, loud snoring, or nocturnal desaturation disproportionate to spirometric findings. Diagnosis relies on overnight polysomnography and arterial blood gas analysis. Management includes optimizing bronchodilator therapy, smoking cessation, and pulmonary rehabilitation. Continuous Positive Airway Pressure (CPAP) remains the cornerstone of treatment, improving oxygenation and survival. Early recognition and integrated management reduce exacerbations, hospitalizations, and cardiovascular complications.
Senior Consultant & Clinical Lead, Pulmonology & Sleep Medicine Apollo Hospitals, Chennai
Dr. Srinivas Rajagopala is a Senior Consultant and Clinical Lead in Pulmonology and Sleep Medicine at Apollo Hospitals, Chennai. He has vast expertise in managing complex respiratory disorders, critical care cases, and sleep-related breathing disorders. With a strong academic and clinical background, Dr. Rajagopala is recognized for his evidence-based approach and excellence in patient care. He is also actively involved in research, teaching, and promoting awareness about respiratory and sleep health.