Description
This webinar provides a comprehensive overview of breast cancer care, covering the entire continuum from early detection and diagnosis to the latest advancements in treatment. Participants will gain insights into updated screening guidelines, imaging modalities, and the role of genetics in risk assessment. The session will also highlight recent progress in surgical techniques, targeted therapies, and personalized oncology. Designed for oncologists, surgeons, and healthcare professionals, it aims to enhance clinical understanding and improve patient outcomes through evidence-based, multidisciplinary approaches.
Summary Listen
- Breast cancer is a significant health issue in India, with alarming statistics of frequent diagnoses and deaths. While more common in women, men can also develop the disease. Early detection and awareness are crucial for improved outcomes.
- The anatomy of the breast is vital for surgical planning and understanding cancer spread. The breast is divided into four quadrants, with the upper lateral being the most common site for cancer development. Lymph node drainage, particularly the axillary nodes, is a key consideration in treatment.
- Breast cancer arises from DNA damage in cells, leading to uncontrolled multiplication and tumor formation. Common clinical features include palpable lumps, skin dimpling, and a peau d'orange appearance. Risk factors range from early menarche and late menopause to obesity, diet, and family history.
- Genetic factors, especially BRCA1 and BRCA2 gene mutations, play a significant role in breast cancer risk. Screening methods include breast self-exams, clinical examinations, mammograms, and ultrasounds. A triple assessment involving clinical examination, breast imaging, and biopsy is recommended for prompt diagnosis.
- The type of biopsy performed impacts treatment decisions. Core needle biopsies or true cut biopsies are preferred over FNAC for better tissue assessment and hormone receptor status evaluation. Molecular classification based on ER, PR, and HER2 status is essential for tailoring treatment plans.
- Treatment for breast cancer involves a multi-disciplinary approach, including surgery, radiotherapy, and systemic treatments like chemotherapy, immunotherapy, and hormonal therapy. Neoadjuvant chemotherapy can be used to downstage the cancer before surgery, improving outcomes.
- Surgical options range from breast-conserving surgery (BCS) to mastectomy, often accompanied by reconstruction. Sentinel lymph node biopsy helps determine the extent of lymph node involvement and guides axillary dissection. Skin-sparing mastectomies with immediate reconstruction are emerging techniques.
- Adjuvant therapies are crucial after surgery, with hormonal therapy used for ER/PR-positive cancers and chemotherapy/targeted therapy used based on HER2 status and other factors. Radiotherapy is often used after BCS and in certain mastectomy cases to reduce recurrence risk.
- Management of metastatic breast cancer depends on hormone receptor and HER2 status, guiding the use of hormonal therapy, targeted therapy, and chemotherapy. Palliative care focuses on improving quality of life and managing symptoms.
Sample Certificate
About the Speakers
Dr. Sarath Kumar Avula
Consultant in Colorectal Surgery & General Surgery, Arete Hospitals, Hyderabad
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