Allergic Bronchopulmonary Aspergillosis (ABPA) is a hypersensitivity reaction to Aspergillus fumigatus seen in patients with asthma or cystic fibrosis. Diagnosis involves clinical suspicion with symptoms like cough, wheezing, and mucus plugs, along with elevated total IgE (>1000 IU/mL), positive Aspergillus-specific IgE/IgG, eosinophilia, and characteristic findings on HRCT chest (central bronchiectasis, mucus impaction). Management focuses on controlling inflammation and fungal burden using oral corticosteroids as first-line therapy, with antifungal agents like itraconazole or voriconazole to reduce fungal load and steroid dependence. Regular monitoring of IgE levels helps assess response and detect relapses early.
Senior Consultant Pulmonologist Associate Director AIG Hospitals, Hyderabad
Dr. Nishant Sinha is a Senior Consultant Pulmonologist and Associate Director at AIG Hospitals, Hyderabad. He specializes in the diagnosis and management of complex respiratory conditions, including asthma, COPD, interstitial lung diseases, and critical care pulmonology. With extensive clinical experience, Dr. Sinha is dedicated to providing patient-centered care and implementing evidence-based treatment strategies. He is also actively involved in mentoring medical professionals and advancing pulmonary medicine through research and education. His expertise and compassionate approach have made him a trusted authority in respiratory health.