Ringkasan
- HPV is a non-enveloped, double-stranded DNA virus with over 200 genotypes, some of which can cause cancers of the cervix, vagina, vulva, penis, anus, and oral cavity. While most people clear HPV infections within 6-12 months, chronic infections can lead to cancer over 15-20 years, influenced by age, parity, STIs, and smoking.
- HPV vaccines are non-infectious, recombinant vaccines made from purified virus-like particles of the L1 protein. They are highly immunogenic, with recipients developing antibodies one month after completing the full vaccination series. Available vaccines include bivalent, quadrivalent, and nonavalent options.
- Dosage recommendations vary. The CDC recommends two doses for ages 9-14 and three doses for ages 15-26. The NHS recommends two doses for ages 12-13 and three doses only for selected individuals. Dubai Health Authority follows a schedule dependent on age, with two doses for 13-14-year-olds and three doses for those older than 15.
- Emerging evidence suggests a single dose schedule can be effective, leading the WHO to recommend one or two doses for girls aged 9-14 and 15-20, and two doses for women older than 21. Contraindications include hypersensitivity to yeast and moderate to severe acute illness.
- Challenges to HPV vaccination include genotyping variations, lack of knowledge about HPV and vaccines, fear about safety and efficacy, cost concerns, lack of time, and negative experiences with vaccinations. Health literacy initiatives and culturally tailored education are crucial for improving uptake.
Contoh Sertifikat
Tentang Pembicara
Dr. Krishi Gowdra Revanna Siddappa
Specialist Obstetrics and Gynecology, Zulekha Hospital
Pengungkapan Keuangan
Komentar
Komentar
Anda harus login untuk meninggalkan komentar.