Keterangan
Gestational diabetes occurs when your body can’t make enough insulin during your pregnancy. During pregnancy, body makes more hormones and goes through other changes, such as weight gain. These changes cause your body’s cells to use insulin less effectively, a condition called insulin resistance. Insulin resistance increases your body’s need for insulin. All pregnant women have some insulin resistance during late pregnancy. However, some women have insulin resistance even before they get pregnant. They start pregnancy with an increased need for insulin and are more likely to have gestational diabetes.
Ringkasan
- The presentation focused on gestational diabetes mellitus, starting with a case study of a 29-year-old pregnant woman with elevated blood sugar levels. The initial question explored differentiating gestational diabetes from overt, pre-gestational, and type 2 diabetes, highlighting the importance of timing and diagnostic criteria.
- Gestational diabetes is defined as diabetes first recognized during pregnancy, typically in the late pregnancy (beyond 24 weeks) due to decreased insulin sensitivity. Overt diabetes, on the other hand, is diagnosed by raised fasting blood glucose, HbA1c, or random blood glucose levels, usually during the first prenatal visit. Pre-gestational diabetes, can be diagnosed at any time during the pregnancy.
- Metabolic changes in gestational diabetes mellitus include accelerated starvation (increased lipolysis in the fasting state), facilitated anabolism (glucose uptake prioritized by the fetus after meals), and circulating islet cell antibodies. Accelerated anabolism is not a characteristic term.
- Diagnostic testing for gestational diabetes mellitus is typically done between 24 and 28 weeks of pregnancy. Different criteria, such as ADA, Carpenter C, and NDDG, have different cut-off values for fasting, 1-hour, 2-hour, and 3-hour glucose levels after a glucose load. A diagnosis requires at least two values to be elevated, adhering to the specific criteria used.
Contoh Sertifikat
Tentang Pembicara
Dokter Swathi
Asisten Profesor, Biokimia, Datta Megha Institute of Medical Sciences, Wardha
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