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Pharmacotherapy of diabetes : Case-based scenarios

Pharmacotherapy for diabetes aims to manage blood glucose levels and prevent complications in individuals with diabetes mellitus. The cornerstone of pharmacotherapy for type 1 diabetes is insulin replacement therapy, which can be delivered through injections or insulin pumps. For type 2 diabetes, oral antidiabetic medications are commonly prescribed, such as metformin, which improves insulin sensitivity and reduces liver glucose production. Sulfonylureas stimulate insulin secretion from the pancreas and are often used in combination with metformin for type 2 diabetes. Thiazolidinediones enhance insulin action in the body's tissues, improving glucose uptake and utilization. Dipeptidyl peptidase-4 (DPP-4) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists increase insulin secretion, decrease glucagon production, and slow gastric emptying. Sodium-glucose co-transporter 2 (SGLT2) inhibitors promote glucose excretion through the urine, leading to reduced blood glucose levels.

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Dr. Bijayraj. R

Founder President of (AFPI)- Kerala Chapter, Consultant Diabetologist, MIMS Hospital

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Dr. Bijayraj. R's Talks on Assimilate

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Dr. Bijayraj. R
  • 3rd-August-2023, TIME : 4:30PM - 5:30PM
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Pharmacotherapy for diabetes aims to manage blood glucose levels and prevent complications in individuals with diabetes mellitus. The cornerstone of pharmacotherapy for type 1 diabetes is insulin replacement therapy, which can be delivered through injections or insulin pumps. For type 2 diabetes, oral antidiabetic medications are commonly prescribed, such as metformin, which improves insulin sensitivity and reduces liver glucose production. Sulfonylureas stimulate insulin secretion from the pancreas and are often used in combination with metformin for type 2 diabetes. Thiazolidinediones enhance insulin action in the body's tissues, improving glucose uptake and utilization. Dipeptidyl peptidase-4 (DPP-4) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists increase insulin secretion, decrease glucagon production, and slow gastric emptying. Sodium-glucose co-transporter 2 (SGLT2) inhibitors promote glucose excretion through the urine, leading to reduced blood glucose levels.