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Approach to Resistant Hypertension
Managing resistant hypertension, a condition where blood pressure remains elevated despite treatment, requires a comprehensive approach. Resistant hypertension is typically defined as high blood pressure that remains uncontrolled despite the use of three or more different antihypertensive medications. The first step in managing resistant hypertension involves lifestyle changes, including adopting a low-sodium diet, regular exercise, weight management, and reducing alcohol intake. Healthcare providers should review current medications to ensure optimal dosing and assess for potential drug interactions or contributing factors. Identifying and treating underlying causes of secondary hypertension, such as kidney disease or hormonal disorders, is crucial. Patients are often encouraged to monitor their blood pressure at home to assess its variability and ensure accurate readings. Using combination therapies that include different classes of antihypertensive drugs can be more effective in controlling resistant hypertension.
About the Speaker
Dr. Lissy George,
Consultant Physician, IQRAA hospital, Calicut, Kerala
Dr. Lissy George is a dedicated and compassionate physician with certification in Internal Medicine and extensive experience in diagnosing and treating multiple disease states and health concerns. She has a strong background working with diverse populations, including resource-limited settings, and a special interest in Preventive medicine, Obstetric Medicine, and academic activities. Dr. George has worked as a general practitioner and a junior medical officer in various hospitals and is currently working as a consultant in General Medicine.
Upcoming Case Discussions
New Approach of treatment of Diabetic Neuropathy
Emerging treatments for diabetic neuropathy focus on addressing the root causes and providing symptomatic relief. Novel therapies include advanced pain management drugs, nerve regeneration techniques, and the use of antioxidants like alpha-lipoic acid. Regenerative medicine approaches, such as stem cell therapy, aim to repair damaged nerves. Personalized treatment plans incorporating lifestyle changes, glycemic control, and physical therapy are gaining importance. These innovative strategies improve quality of life and target long-term nerve health in diabetic patients.
Alpha Lipoic Acid in Oxidative Stress
Alpha-lipoic acid (ALA) is a potent antioxidant that helps combat oxidative stress by neutralizing free radicals. It regenerates other antioxidants like vitamin C and E, enhancing overall antioxidant defense. ALA plays a crucial role in reducing cellular damage caused by conditions like diabetes, neuropathy, and aging. Its ability to function in both water- and fat-soluble environments makes it versatile in protecting various tissues. Regular supplementation of ALA may improve mitochondrial function and reduce inflammation associated with oxidative stress.
Evaluating Cardiac Function in Sepsis and Septic Shock
Cardiac dysfunction is common in sepsis and septic shock, requiring careful evaluation for optimal management. Echocardiography is the cornerstone for assessing myocardial function, including ejection fraction and cardiac output. It detects ventricular dilation, reduced contractility, or other abnormalities. Biomarkers like troponins and B-type natriuretic peptide (BNP) help identify myocardial injury and stress. Hemodynamic monitoring, using tools like pulmonary artery catheters or pulse contour analysis, provides insights into cardiac output and systemic vascular resistance. Early identification of cardiac dysfunction enables tailored interventions.
Clinician’s Approach to Acute Respiratory Distress Syndrome
A clinician’s approach to respiratory infections involves a thorough assessment of symptoms, patient history, and risk factors, followed by diagnostic testing such as sputum cultures, chest X-rays, or PCR tests to identify the causative pathogen. Based on the diagnosis, appropriate antimicrobial therapy, supportive care, and close monitoring for complications are initiated, with attention to managing comorbid conditions and preventing the spread of infection.
Cancer and Air Pollution: The Delhi Dilemma
Cancer and air pollution are deeply intertwined in Delhi, where pollution levels rank among the highest globally. Prolonged exposure to particulate matter and carcinogenic toxins in the air increases the risk of respiratory and lung cancers. The city's residents face a significant health burden, particularly vulnerable groups like children and the elderly. Addressing this challenge requires stringent pollution control measures, public health awareness, and policy interventions. The Delhi dilemma underscores the urgent need for sustainable urban planning and environmental regulations to protect public health.