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Acute complications of Diabetes: Ketoacidosis and its management
When your body produces a lot of the blood acids known as ketones, or ketones, it can lead to a serious complication of diabetes called diabetic ketoacidosis. When your body can't create enough insulin, the problem sets in. Sugar (glucose), a main source of energy for your muscles and other tissues, generally enters your cells with the aid of insulin. Insufficient insulin causes your body to start using fat as fuel. If left untreated, this process results in a buildup of acids in the blood called ketones, which eventually cause diabetic ketoacidosis. In diabetic ketoacidosis patients, the fluid deficit may be as much as 10% to 15% of body weight. Immediate fluid resuscitation is essential to treat hypovolemia, restore tissue perfusion, and clear ketones. Independent of insulin, hydration enhances glycemic control.
About the Speaker
Assistant Professor,Biochemistry,Datta Megha Institute of Medical Sciences, Wardha
Primary Adrenal Insufficiency: A Case Study & Review of Literature
Autoimmune Addison disease affects the function of the adrenal glands, which are small hormone-producing glands located on top of each kidney. It is classified as an autoimmune disorder because it results from a malfunctioning immune system that attacks the adrenal glands. As a result, the production of several hormones is disrupted, which affects many body systems. The signs and symptoms of autoimmune Addison disease can begin at any time, although they most commonly begin between ages 30 and 50. Common features of this condition include extreme tiredness (fatigue), nausea, decreased appetite, and weight loss. In addition, many affected individuals have low blood pressure (hypotension), which can lead to dizziness when standing up quickly; muscle cramps; and a craving for salty foods. A characteristic feature of autoimmune Addison disease is abnormally dark areas of skin (hyperpigmentation), especially in regions that experience a lot of friction, such as the armpits, elbows, knuckles, and palm creases. The lips and the inside lining of the mouth can also be unusually dark. Because of an imbalance of hormones involved in development of sexual characteristics, women with this condition may lose their underarm and pubic hair.
Diabetes in critically ill patient
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Cardiometabolic case on Diabetes: Know Diabetes By Heart
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