0.4 CME

الوقاية من العدوى المكتسبة في وحدة العناية المركزة وإدارتها

المتحدث: الدكتور د. ساي راما ديفي

دكتور في الطب، عضو في IDCCM، عضو في EDIC، ماجستير في إدارة الأعمال، استشاري العناية الحرجة في مستشفى أبولو، فيساخاباتنام

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وصف

ICU (Intensive Care Unit) acquired infections are a significant concern in healthcare settings. These infections can lead to prolonged hospital stays, increased healthcare costs, and even mortality. Preventing and managing ICU acquired infections is essential to ensure the safety of patients and healthcare workers. They can be caused by a variety of microorganisms, including bacteria, viruses, and fungi. The most common ICU acquired infections include pneumonia, bloodstream infections, and urinary tract infections. ICU patients are at higher risk for infections due to their weakened immune systems, exposure to invasive procedures, and prolonged hospital stays. Hand hygiene is the most effective way to prevent the spread of infections in healthcare settings. Personal protective equipment (PPE), such as gloves, gowns, and masks, should be used when necessary to prevent the transmission of infections. Transmission-based precautions are used for patients with known or suspected infectious diseases and include contact, droplet, and airborne precautions.

ملخص

  • Nosocomial infections, or hospital-acquired infections, are infections patients contract during their healthcare stay, typically manifesting 48-72 hours after admission. These infections are significant due to their contribution to morbidity and mortality, caused by highly pathogenic microorganisms. They increase a patient's length of stay and associated healthcare costs.
  • The source of these infections can be the hospital staff, directly transmitting the infection, or hospital equipment and devices, which cause indirect infection. These infections are distinct from community-acquired infections, as they are often caused by drug-resistant organisms requiring stronger antibiotics and involving multiple organ systems. Common culprits include *Escherichia coli*, *Pseudomonas aeruginosa*, *Klebsiella*, *Acinetobacter*, *Clostridium*, and *Candida albicans*.
  • Infection control involves a multi-step process, including assessing the need for isolation, identifying patients at risk, educating staff on hand hygiene, implementing standard and transmission-based precautions, and considering environmental factors. Isolation is crucial for immunocompromised patients, those with specific diseases, or carriers of epidemic strains.
  • Isolation types include positive pressure isolation, which protects immunocompromised patients by maintaining higher pressure within the room to prevent outside contaminants from entering, and negative pressure isolation, used for airborne infections like tuberculosis or COVID-19, where lower pressure inside the room prevents infectious particles from escaping.
  • Hand hygiene is a cornerstone of prevention. The "five moments" for hand hygiene are before touching a patient, before a clean procedure, after body fluid exposure, after touching a patient, and after touching the patient's surroundings. Either antimicrobial soap and water (for visible contamination) or alcohol-based hand rubs (for routine contact) should be used.
  • Standard precautions are universal measures, while specific precautions are tailored to particular diseases or agents. Contact precautions require gowns, gloves, masks, and eye protection to prevent direct or indirect contact with infected patients. Airborne precautions, for diseases like tuberculosis, necessitate negative pressure isolation and respiratory protection. Droplet precautions address infections spread by larger droplets within a 6-10 feet radius, requiring respiratory protection.
  • ICU-specific strategies focus on preventing line-related infections, catheter-associated urinary tract infections (CAUTI), ventilator-associated pneumonia (VAP), surgical site infections (SSI), and pressure sores. Early removal of devices is key.
  • VAP prevention includes elevating the head of the bed, providing oral care with a toothbrush, daily sedation vacation, DVT prophylaxis, and peptic ulcer disease prophylaxis. Nursing-driven protocols assessing readiness for extubation are crucial. Early and late VAP differ in organisms and antibiotic susceptibility.
  • CAUTI prevention involves sterile insertion techniques, maintaining a closed drainage system, using smaller catheters, proper catheter placement, and timely removal reminders. Foley catheter necessity must be documented daily, and specimens should only be collected when clinically indicated. Asymptomatic bacteriuria should generally not be treated.
  • Central line-associated bloodstream infections (CLABSI) prevention includes hand hygiene, maximal barrier precautions, chlorhexidine skin antisepsis, optimal site selection (avoiding femoral veins), and catheter necessity assessment. Management involves culturing the line and peripheral blood and treating with appropriate antibiotics based on identified organisms.
  • Pressure sore prevention includes using appropriate support surfaces, frequent inspection and repositioning, moisture control, and proper nutrition and hydration. The Braden Scale assesses risk. Surgical site infections require pre-operative bathing, appropriate antibiotic prophylaxis, and proper hair removal techniques.
  • Antibiotic stewardship is crucial to prevent *Clostridium difficile* infections and multi-drug resistant organisms. It involves enhancing infection prevention, prescribing antibiotics only when truly needed, appropriate antibiotic selection, dosage, duration, and re-assessing antibiotic use based on culture results.
  • Environmental factors are also vital. High-quality cleaning and disinfection of patient care areas with approved detergents and disinfectants are essential. Surfaces should be cleaned regularly, with terminal cleaning performed after each patient discharge.
  • Organizational support is crucial, including maintaining appropriate nurse-to-patient ratios, controlling traffic flow, implementing proper waste disposal policies, providing staff education and training, and establishing infection control policies and teams.
  • Architectural layout also plays a role, with ICUs located close to operating rooms and away from main ward areas, proper air filtration and air changes, clearly demarcated traffic routes, adequate space between beds, and adequate facilities like scrub areas and clean storage.

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