0.32 سم مكعب

تحسين النتائج في الحمل خارج الرحم

المتحدث: الدكتور كريشنا كوماري

Senior Consultant Gynecologist, Apollo Hospital, Hyderabad

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وصف

Ectopic pregnancy occurs when a fertilized egg implants outside of the uterus, most commonly in the fallopian tubes. Optimizing outcomes in ectopic pregnancy is crucial to ensure the health and well-being of the mother. Early detection is key to optimizing outcomes in ectopic pregnancy, as it allows for prompt intervention and treatment. Transvaginal ultrasound is a valuable tool for diagnosing ectopic pregnancy and determining the location of the embryo. Medical management with methotrexate, a medication that stops the growth of the embryo, can be an effective non-surgical option in certain cases. Surgical intervention, such as laparoscopic surgery, is often necessary to remove the ectopic pregnancy and repair any damage to the fallopian tubes. Timely surgical intervention helps minimize the risk of complications and improve outcomes. Close monitoring of hCG levels (a hormone produced during pregnancy) is important to ensure that the treatment is effective and the pregnancy is resolving. Treating any underlying conditions, such as pelvic inflammatory disease, can reduce the risk of ectopic pregnancy. Follow-up care is essential to monitor the patient's physical and emotional recovery after ectopic pregnancy.

ملخص

  • Ectopic gestation is a critical obstetrical issue that can be easily overlooked, requiring consideration in all reproductive-age women, regardless of menstrual regularity or contraceptive use. It involves pregnancy implantation outside the uterine cavity, with the most common site being the fallopian tube. Less frequent locations include the ovaries, abdomen, cervix, and, increasingly, cesarean section scars.
  • Diagnosis can be challenging, as one-third of ectopic pregnancies are incidentally discovered. The classic triad includes amenorrhea, vaginal bleeding, and abdominal pain, but symptoms vary. Patients may present with irregular bleeding, spotting, or shoulder tip pain indicating internal bleeding. Syncopal attacks and signs of shock may also occur.
  • Initial management focuses on stabilizing hemodynamically unstable patients, with resuscitation and rapid surgical intervention considered. For stable patients, a thorough history, physical examination, lab tests, and ultrasound are essential. Key historical factors include menstrual history, previous pregnancies or surgeries, contraceptive use, and history of pelvic inflammatory disease (PID).
  • Ultrasound plays a vital role in confirming the diagnosis. Early in pregnancy, the gestational sac appears around five weeks, followed by the yolk sac. Absence of an intrauterine sac despite a positive hCG suggests an ectopic pregnancy, sometimes requiring serial hCG measurements to differentiate it from a pregnancy of unknown location (PUL). Heterotopic pregnancy, involving simultaneous intrauterine and ectopic pregnancies, should also be considered, especially after IVF.
  • Management options include expectant, medical, and surgical approaches. Expectant management is suitable when hCG levels are falling. Medical management with methotrexate is effective for stable patients with low hCG levels, no cardiac activity, and good follow-up compliance. Surgical intervention, either salpingostomy or salpingectomy, is considered when medical management fails or in unstable conditions.
  • Rare sites of ectopic pregnancy, such as ovarian and cesarean scar pregnancies, present unique challenges. Cesarean scar pregnancies can lead to placenta accreta, scar rupture, and intraabdominal bleeding. Management involves methotrexate and surgical removal, often requiring uterine artery embolization or ligation. Rh incompatibility should always be considered, and Rh-negative women should receive Rh immunoglobulin.
  • Future recurrence risk is approximately 15%. Chlamydia is a significant risk factor due to its association with subclinical salpingitis. Following cornual or cesarean scar pregnancy repair, future pregnancies carry a higher risk of rupture. Early monitoring in subsequent pregnancies is crucial. In cases of recurrent ectopic pregnancy, salpingectomy may be advised before proceeding with IVF.

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