ملخص
- Reviews of intermittent fasting interventions show improvements in quality of life, psychosocial well-being, physical well-being, and reduced fatigue. Current studies focus on cancer cell sensitivity to food and fasting, and the implications for cancer prevention and treatment. Calorie restriction can impact cancer growth and development, potentially enhancing chemotherapy and radiation therapy efficiency.
- Intermittent fasting's effect on lipid metabolism can decrease LDL cholesterol and triglycerides. Fasting can also reduce ammonia concentration while keeping nitrogen concentration relatively constant. Regarding glucose metabolism, studies using intermittent energy restriction have shown controlled blood glucose and decreased HbA1c, while early time-restricted feeding improved insulin sensitivity and cell responsiveness.
- Intermittent fasting induces metabolic conversion, shifting from glucose to fatty acids as the primary energy source. Triglycerides break down into fatty acids, and the liver converts these into ketone bodies, which become the brain's main energy source. Blood ketone body levels increase after 8-12 hours of fasting.
- A study of chemotherapy patients with breast and ovarian cancer reported improved quality of life and reduced tiredness after 8 hours of treatment, following short-term fasting. Another study revealed that fasting for less than 13 hours per night was associated with a higher risk of breast cancer recurrence.
- While safe for many, intermittent fasting isn't for everyone. It's not recommended for cancer patients who are pregnant, breastfeeding, young children, older adults experiencing weakness, patients with immunodeficiencies, current or past eating disorders, dementia, traumatic brain injury, diabetes, or kidney stones. Potential risks include hunger, cravings, insomnia, fatigue, nausea, headache, digestive issues, and malnutrition.
- Medical guidance is crucial for ensuring safety, providing personalized guidance, comprehensive care, and a collaborative approach. It is important to align the regimen with the treatment goals and to be aware of the treatment plans that the patient is receiving.
- Implementing intermittent fasting should be gradual, considering meal timings in relation to treatments. Hydration and nutrient-dense food sources are essential. Monitoring, psychological support, and collaboration with the healthcare team are important. Patients should listen to their body signals and communicate any changes in their well-being.
- The pre-treatment phase involves assessing overall health and nutritional status, educating patients on benefits and risks, and collaborating with the healthcare team. During treatment, patients should be monitored closely and their fasting protocol should be adjusted accordingly. In the post-treatment phase, the patient should have a gradual transition back to a regular eating pattern.
- A personalized approach is important to suit individual needs, considering factors like biology, lifestyle, and preferences, which can boost patient satisfaction.
نموذج شهادة
حول المتحدثين
Ms. Noor Farouk Abu Dheir
Clinical Dietician (Oncology and bone marrow transplant), Burjeel Medical City MBZ
الإفصاح المالي
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