- 54k views
Systemic Lupus Erythematosus (SLE)
Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease that can affect various parts of the body, including the skin, joints, kidneys, heart, lungs, brain, and blood vessels. In SLE, the body's immune system mistakenly attacks its own tissues, leading to inflammation and damage. The exact cause of SLE is not fully understood, but it is believed to involve a combination of genetic, environmental, and hormonal factors.One of the hallmark features of SLE is its wide range of symptoms, which can vary greatly from person to person and can also fluctuate over time. Common symptoms include fatigue, joint pain and stiffness, skin rashes (such as the classic "butterfly" rash across the cheeks and nose), fever, photosensitivity (sensitivity to sunlight), hair loss, mouth ulcers, and chest pain with deep breathing.SLE can also cause complications in various organs and systems of the body. For example, inflammation of the kidneys (known as lupus nephritis) can lead to kidney damage and impaired function. Inflammation of the heart and blood vessels can increase the risk of cardiovascular disease. Inflammation of the brain and nervous system can cause headaches, confusion, seizures, and other neurological symptoms.
About the Speaker

Dr. Shanmuganandan Krishnan
Professor SBMCH, Consultant Rheumatology, Apollo Hospitals, Chennai
Brig (Prof.) Krishnan. Shanmuganandan, a distinguished medical professional, brings over 30 years of extensive teaching and clinical experience to the field of medicine. With a robust academic background including an MBBS and MD in Medicine from AFMC, as well as specialized training in Rheumatology, HIV Medicine, and Health Research Methodology, he has continuously contributed to medical education and research. Currently serving as a Professor at SBMCH/BIHER and a Consultant Rheumatologist at prestigious institutions such as Apollo Hospitals and Rela Hospitals in Chennai, Dr. Shanmuganandan excels in clinical problem-solving and diagnosis. His expertise extends to digital health, biosimilar use, immunoinflammatory syndromes, and post-COVID hyperinflammatory immune syndromes. A recipient of commendation medals and awards, he has also been actively involved in editorial roles, MCI assessment, and various professional associations, showcasing his commitment to advancing medical knowledge and healthcare practices in India.
Upcoming Case Discussions
Impact of Endometriosis on Fertility
Endometriosis, a condition where endometrial-like tissue grows outside the uterus, can significantly impact fertility. It causes inflammation, scarring, and adhesions that may distort pelvic anatomy, block fallopian tubes, and impair ovarian function. Endometriosis is also linked to hormonal imbalances and poor egg quality, reducing the chances of conception. Symptoms like chronic pelvic pain and painful intercourse further complicate fertility. Diagnosis often requires laparoscopy, while management includes pain relief, hormonal therapy, and assisted reproductive techniques like IVF. Early intervention with medical or surgical treatment can improve reproductive outcomes, but severe cases may necessitate advanced fertility treatments for conception.
Hyperlipidemia: From Diagnosis to Treatment
Hyperlipidemia is a condition characterized by elevated levels of lipids, such as cholesterol and triglycerides, in the blood, which can increase the risk of cardiovascular diseases. Diagnosis typically involves blood tests measuring lipid profiles, while treatment focuses on lifestyle changes, such as diet and exercise, alongside medications like statins to manage cholesterol levels and reduce cardiovascular risk. Regular monitoring is essential for effective management and prevention of complications.
Acne: Disorders and Treatment Approaches
Acne is a common dermatological condition caused by clogged pores, excess sebum production, bacterial growth, and inflammation. It can manifest as blackheads, whiteheads, papules, pustules, or cysts, often leading to scarring if untreated. Various factors, including hormonal changes, diet, stress, and genetics, influence its severity. Treatment approaches range from topical and oral medications, such as retinoids, antibiotics, and hormonal therapy, to advanced procedures like chemical peels and laser therapy. A personalized skincare regimen, along with lifestyle modifications, plays a crucial role in managing and preventing acne.
Lung Ultrasound in Acute Respiratory Failure
Lung ultrasound has emerged as a vital, non-invasive tool in the rapid assessment of acute respiratory failure. It provides real-time imaging to differentiate conditions like pneumonia, pulmonary edema, pneumothorax, and pleural effusion with high accuracy. Compared to traditional chest X-rays, lung ultrasound offers superior sensitivity, especially in critically ill patients where bedside evaluation is crucial. Its ability to guide immediate clinical decisions improves patient outcomes and reduces unnecessary radiation exposure. With standardized protocols like the BLUE (Bedside Lung Ultrasound in Emergency) protocol, it enhances diagnostic efficiency in emergency and ICU settings.
Gallstone Disease & Cholecystitis: When to Operate?
iGallstone disease and cholecystitis are common conditions requiring careful evaluation to determine the need for surgery. Symptomatic gallstones causing recurrent pain, nausea, or complications like cholecystitis often necessitate cholecystectomy. Acute cholecystitis, characterized by inflammation, fever, and right upper quadrant pain, typically requires early surgical intervention to prevent complications like perforation or sepsis. In high-risk patients, conservative management with antibiotics and drainage may be considered. Elective surgery is recommended for asymptomatic patients with high-risk factors, such as large gallstones or gallbladder polyps, to prevent future complications.