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Pharmacotherapy of diabetes : Case-based scenarios
Pharmacotherapy for diabetes aims to manage blood glucose levels and prevent complications in individuals with diabetes mellitus. The cornerstone of pharmacotherapy for type 1 diabetes is insulin replacement therapy, which can be delivered through injections or insulin pumps. For type 2 diabetes, oral antidiabetic medications are commonly prescribed, such as metformin, which improves insulin sensitivity and reduces liver glucose production. Sulfonylureas stimulate insulin secretion from the pancreas and are often used in combination with metformin for type 2 diabetes. Thiazolidinediones enhance insulin action in the body's tissues, improving glucose uptake and utilization. Dipeptidyl peptidase-4 (DPP-4) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists increase insulin secretion, decrease glucagon production, and slow gastric emptying. Sodium-glucose co-transporter 2 (SGLT2) inhibitors promote glucose excretion through the urine, leading to reduced blood glucose levels.
About the Speaker
Dr. Bijayraj. R
Founder President of (AFPI)- Kerala Chapter, Consultant Diabetologist, MIMS Hospital
Upcoming Case Discussions
Impact of Endometriosis on Fertility
Endometriosis, a condition where endometrial-like tissue grows outside the uterus, can significantly impact fertility. It causes inflammation, scarring, and adhesions that may distort pelvic anatomy, block fallopian tubes, and impair ovarian function. Endometriosis is also linked to hormonal imbalances and poor egg quality, reducing the chances of conception. Symptoms like chronic pelvic pain and painful intercourse further complicate fertility. Diagnosis often requires laparoscopy, while management includes pain relief, hormonal therapy, and assisted reproductive techniques like IVF. Early intervention with medical or surgical treatment can improve reproductive outcomes, but severe cases may necessitate advanced fertility treatments for conception.
Hyperlipidemia: From Diagnosis to Treatment
Hyperlipidemia is a condition characterized by elevated levels of lipids, such as cholesterol and triglycerides, in the blood, which can increase the risk of cardiovascular diseases. Diagnosis typically involves blood tests measuring lipid profiles, while treatment focuses on lifestyle changes, such as diet and exercise, alongside medications like statins to manage cholesterol levels and reduce cardiovascular risk. Regular monitoring is essential for effective management and prevention of complications.
Acne: Disorders and Treatment Approaches
Acne is a common dermatological condition caused by clogged pores, excess sebum production, bacterial growth, and inflammation. It can manifest as blackheads, whiteheads, papules, pustules, or cysts, often leading to scarring if untreated. Various factors, including hormonal changes, diet, stress, and genetics, influence its severity. Treatment approaches range from topical and oral medications, such as retinoids, antibiotics, and hormonal therapy, to advanced procedures like chemical peels and laser therapy. A personalized skincare regimen, along with lifestyle modifications, plays a crucial role in managing and preventing acne.
Lung Ultrasound in Acute Respiratory Failure
Lung ultrasound has emerged as a vital, non-invasive tool in the rapid assessment of acute respiratory failure. It provides real-time imaging to differentiate conditions like pneumonia, pulmonary edema, pneumothorax, and pleural effusion with high accuracy. Compared to traditional chest X-rays, lung ultrasound offers superior sensitivity, especially in critically ill patients where bedside evaluation is crucial. Its ability to guide immediate clinical decisions improves patient outcomes and reduces unnecessary radiation exposure. With standardized protocols like the BLUE (Bedside Lung Ultrasound in Emergency) protocol, it enhances diagnostic efficiency in emergency and ICU settings.
Gallstone Disease & Cholecystitis: When to Operate?
iGallstone disease and cholecystitis are common conditions requiring careful evaluation to determine the need for surgery. Symptomatic gallstones causing recurrent pain, nausea, or complications like cholecystitis often necessitate cholecystectomy. Acute cholecystitis, characterized by inflammation, fever, and right upper quadrant pain, typically requires early surgical intervention to prevent complications like perforation or sepsis. In high-risk patients, conservative management with antibiotics and drainage may be considered. Elective surgery is recommended for asymptomatic patients with high-risk factors, such as large gallstones or gallbladder polyps, to prevent future complications.
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Dr. Bijayraj. R's Talks on Assimilate
- 3rd-August-2023, TIME : 4:30PM - 5:30PM
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Pharmacotherapy for diabetes aims to manage blood glucose levels and prevent complications in individuals with diabetes mellitus. The cornerstone of pharmacotherapy for type 1 diabetes is insulin replacement therapy, which can be delivered through injections or insulin pumps. For type 2 diabetes, oral antidiabetic medications are commonly prescribed, such as metformin, which improves insulin sensitivity and reduces liver glucose production. Sulfonylureas stimulate insulin secretion from the pancreas and are often used in combination with metformin for type 2 diabetes. Thiazolidinediones enhance insulin action in the body's tissues, improving glucose uptake and utilization. Dipeptidyl peptidase-4 (DPP-4) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists increase insulin secretion, decrease glucagon production, and slow gastric emptying. Sodium-glucose co-transporter 2 (SGLT2) inhibitors promote glucose excretion through the urine, leading to reduced blood glucose levels.