विवरण
Embarking on a journey through a career and research in women's Gastroenterology health is a dynamic exploration of advancing medical knowledge and improving patient outcomes. This path involves a commitment to understanding the intricacies of gastrointestinal issues unique to women, fostering expertise in areas such as pregnancy-related digestive concerns, hormonal influences on gastrointestinal health, and gender-specific considerations in colorectal diseases. Engaging in continuous research endeavors allows professionals to contribute to the evolving landscape of women's Gastroenterology, addressing unmet needs and paving the way for innovative and tailored healthcare solutions. The journey encompasses a blend of clinical practice, academic pursuit, and a dedication to enhancing the well-being of women through comprehensive gastrointestinal care.
सारांश
- Dr. Khabiba Safar, Dean of the College of Medicine and Health Sciences at Khalifa University, discussed her career path from a DNA expert at Dubai Police to a professor of genomics. She emphasized the importance of building research infrastructure in Abu Dhabi, focusing on genomic sequencing and bioinformatics analysis to support precision medicine. She aimed to leverage OMIX data (genomics, metabolomics, etc.) to better understand disease risk factors and develop preventative measures.
- Dr. Safar detailed the establishment of the Emirates Family Registry, a disease registry to collect blood samples for DNA extraction and sequencing. This involved linking genotype (genetic data) with phenotype (traits and lifestyle) to identify individuals at high risk of chronic diseases like type 2 diabetes. By identifying genes early, individuals could make lifestyle changes to delay disease complications.
- The Biotechnology Center at Khalifa University boasts ISO accreditation and serves as a licensed training facility for graduate and undergraduate students in clinical genetics and molecular biology. It also operated as a diagnostic lab during COVID, manufacturing reagents to address supply chain shortages. Projects include personalized medicine for type 2 diabetes, addiction genetics, and cancer genomics.
- Dr. Safar highlighted collaborative projects, including a cancer project with SSMC and a translational medicine initiative with Ku Leuven in Belgium. These collaborations aim to identify novel genes associated with diseases and develop targeted treatments. The UAE's population diversity necessitated the creation of a local reference genome, leading to the Emirati Genome Project, which initially sequenced 100 individuals and has now expanded to 50,000.
- The COVID-19 pandemic saw Dr. Safar's team contributing to research on variants, cytokine responses, and the role of Vitamin D. They also monitored wastewater to predict infection waves, informing lockdown measures. Dr. Safar's team also focused on translating research findings into commercialization, developing a bone marrow transplant matching chip and a thyroid cancer diagnostic chip.
- Dr. Safar's career involved challenges such as securing funding, finding collaborators, navigating ethical review boards, acquiring lab resources, and recruiting qualified personnel. She emphasized the importance of interdisciplinary collaborations, building trust with collaborators, and focusing on relevant, high-prevalence issues in the region. The talk concluded with Dr. Safar emphasizing the importance of the team, and dedication to achieving results.
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