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मधुमेह में ग्लूकोज निगरानी में नवाचार

वक्ता: डॉ. जे.जयप्रकाशसाई

Senior General Physician, Diabetologist, Apollo Sugar Clinics, Hyderabad

लॉगिन करें प्रारंभ करें

विवरण

Continuous Glucose Monitoring (CGM) devices have revolutionized diabetes management by providing real-time glucose readings, eliminating the need for finger-pricking. Advances in CGM technology have led to smaller, more discreet sensors that can be worn for longer periods, improving patient compliance. Non-invasive glucose monitoring techniques, such as wearable patches and smartwatches, are emerging as promising alternatives to traditional blood-based methods. Integration of CGM data with smartphone apps and cloud-based platforms allows patients to track their glucose levels, analyze trends, and share data with healthcare providers for better personalized care. Implantable CGM sensors are being developed, which can provide long-term glucose monitoring without the need for frequent sensor replacements. Closed-loop insulin delivery systems, also known as artificial pancreas systems, use CGM data to automatically adjust insulin doses, leading to tighter glucose control.

सारांश

  • Blood glucose monitoring is essential in managing diabetes, and continuous glucose monitoring (CGM) is a significant advancement, offering insights beyond HbA1c, which reflects long-term glycemia. CGM helps understand daily glucose fluctuations, crucial for personalized management and reducing complications. Time in range (TIR) is a vital metric, as suboptimal TIR can lead to micro and macrovascular complications, impacting the quality of life for diabetic patients.
  • India faces a significant diabetes burden, with an estimated 100 million diabetic and another 100 million pre-diabetic individuals, emphasizing the need for early diagnosis and effective management. Early glycemic control through lifestyle changes and technology like CGM can have a long-term impact by preventing complications through metabolic memory. Glycemic variability, especially in type 1 diabetes, poses challenges, and international guidelines now recommend using TIR and glycemic variability as key metrics in clinical management.
  • CGM provides comprehensive data on glucose variability, including time spent above and below the target range, aiding in optimizing treatment strategies. Maintaining a TIR of at least 70%, minimizing hypoglycemia, and limiting time above 300 mg/dL can significantly reduce diabetes-related complications. A target range of 110-180 mg/dL postprandial, with fasting below 110 mg/dL, is desirable.
  • Suboptimal TIR negatively impacts the quality of life, increases the risk of acute events, and raises the likelihood of microvascular complications, even affecting cardiovascular mortality. CGM can assist in tailoring insulin dosages for type 1 diabetes, monitoring dietary impact, assessing exercise effects, and potentially reducing oral agent or insulin doses in type 2 diabetes. CGM empowers patients through clear data and promotes lifestyle adjustments related to diet and exercise.
  • The Guardian Connect system from Medtronic is an innovative app-based CGM that provides real-time glucose readings and alerts for high and low glucose levels, allowing remote monitoring by caregivers. The system includes a sensor, transmitter, and software that interconnect to display glucose trends and provide alerts. While it works for one week, it helps monitor glucose levels and send alerts to patients and caretakers about high and low readings.
  • The Libre system from Abbott provides two-week sensor-based glucose monitoring, helping patients and healthcare providers understand glucose fluctuations. Healthcare providers use the data to adjust medications and counsel patients on lifestyle changes, improving diabetes management. It's valuable for early diabetes diagnosis, empowering patients to manage their glucose levels and reduce complications.
  • CGM is not only beneficial for patients on insulin but also for those using oral agents, helping tailor medication and lifestyle interventions based on real-time glucose data. CGM data can help to identify the impacts of food choices and sleep patterns on glucose levels. CGM has application in gestational diabetes for ensuring tight control of glucose levels.
  • Personal experience with CGM is crucial for both patients and healthcare providers, fostering a deeper understanding of individual responses to treatment and lifestyle changes. Holistic management, encompassing diet, exercise, medication, and stress management, is emphasized for optimal outcomes. For managing hypoglycemia, rapid-acting glucose sources or glucagon injections may be required, followed by monitoring and observation. There isn't an ideal time to initiate CGM; the key is selecting the appropriate patient and providing ongoing support and education.

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