विवरण
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in diabetes mellitus. This narrative analysis provides a thorough examination of the intricate relationship between diabetes and cardiovascular problems. Let us synthesize current literature to examine the most recent information on preventative measures and treatment choices for reducing cardiovascular risk in diabetic people. Insulin resistance is a key link between diabetes and CVD, causing dyslipidemia and atherogenesis. As a result, those with diabetes are at a much higher risk of cardiovascular events. Furthermore, hyperglycemia-induced oxidative stress and inflammation worsen endothelial dysfunction and vascular damage, increasing the risk of cardiovascular problems. The combination between diabetes and CVD frequently accelerates the development of atherosclerotic plaque, making the plaque more prone to rupture. This can lead to severe cardiovascular events such as myocardial infarction and stroke.
सारांश
- Type 2 diabetes significantly elevates cardiovascular disease risk, contributing to increased mortality. Emerging risk factors exacerbate complications, including non-fatal myocardial infarction, ischemic and hemorrhagic cerebrovascular accidents. The duration of diabetes directly correlates with cardiovascular disease risk, diminishing life expectancy when combined with cardiovascular events.
- Intensive glycemic control may benefit healthier individuals by mitigating macrovascular risks. Studies have demonstrated that adequate glucose control can lead to positive outcomes. However, prior landmark trials reveal that intensive glucose control improves outcomes related to coronary heart disease events and stroke, but does not affect all-cause mortality.
- Macrovascular risk reduction in type 2 diabetes necessitates a holistic approach extending beyond glucose management. Effective strategies include blood pressure control, cholesterol management (addressing dyslipidemia), smoking cessation, and lifestyle modifications. Aspirin therapy can also be considered to modify cardiovascular risk. Glycemic control is important, but it is not the only parameter.
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