विवरण
The development of gut microbiota in early life is influenced significantly by early infancy feeding practices, including breast milk, formula milk, and the introduction of solid foods. Standard diets such as the Mediterranean, Japanese, Nordic, and Atlantic diets shape the gut microbiota in children, while special diets tailored for conditions like cow milk allergy, FGIDs, and inborn errors of metabolism have unique impacts on gut health. Dietary diversity plays a crucial role in determining the composition and function of the gut microbiome, with strategies aimed at promoting a healthy gut microbiome through tailored dietary interventions showing promise. Case studies and clinical evidence highlight the effectiveness of these dietary interventions in enhancing gut health, pointing to future directions in research and application for optimizing gut microbiota through diet.
सारांश
- The gut microbiome is a critical microbial organ, hosting a vast ecosystem with the highest microbial density in the colon. Its development begins in utero and rapidly changes after birth, influenced by various factors including dietary changes. Maintaining a healthy gut microbiota is essential for a child's optimal growth and development, as it supports gut permeability, nutrient absorption, and prevents pathogenic colonization.
- Targeted strategies aim to modify specific elements of the gut microbiota, while untargeted approaches like exercise and individual nutrition promote general improvement. Imbalances in the gut microbiota can lead to dysbiosis, contributing to various diseases. The first thousand days are crucial for immune development, with a normal gut microbiota playing a key role.
- The gut microbiome also plays a crucial part in immunity and its development in child growth. Healthy microbes consume dietary fiber and carbohydrates, maintaining tight junctions and preventing harmful organism permeability. Nonatopic children have more beneficial bacteria compared to attopic children.
- The gut-brain axis is a bidirectional pathway where the brain influences the gut, and vice versa. Alterations in the gut can lead to changes in stress, anxiety, and mood. Maintaining healthy gut also supports bone health through short chain fatty acids.
- Prebiotics, like galacto-oligosaccharides and fructo-oligosaccharides, can modify gut microbiota composition and function. The combination of L. reuteri and prebiotics has shown beneficial effects in children's gut health, which can further help with management of gastrointestinal disorders.
- L. reuteri DSM 17938, when combined with GOS, FOS is also good for height and bone strength which also showed to reduce the duration of diarrhea with reduced hospital stay time. Further showing that this probiotic represents a viable strategy for preventing gastro intestinal issues.
नमूना प्रमाण पत्र
वक्ताओं के बारे में
Dr. Subhash Rao
Senior Consultant Pediatrician, Fortis Hiranandani Hospital, Mumbai
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