0,53 CME

Techniques de gestion des gaz du sang artériel

Conférencier: Dr Manimala Rao

Head Anaesthesiology & Critical Care,Director Crtical Care,Yashoda

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Description

ABG (Arterial Blood Gas) Management Techniques play a crucial role in assessing a patient's acid-base balance and respiratory status. Proper management of ABGs helps in understanding the respiratory and metabolic status of a patient. The first step in ABG management is collecting an arterial blood sample. Arterial blood samples are typically obtained from the radial artery. A heparinized syringe is used to collect arterial blood samples to prevent clotting. It is crucial to ensure proper patient identification before collecting an arterial blood sample. After obtaining the arterial blood sample, it should be placed on ice and transported to the laboratory promptly.

ABG samples should be analyzed within 30 minutes of collection to obtain accurate results. The partial pressure of carbon dioxide (PaCO2) is measured to evaluate the patient's ventilation status. The bicarbonate (HCO3-) level is measured to assess the metabolic component of acid-base balance.

Résumé

  • The speaker discusses the historical figures who paved the way for understanding blood gas analysis, highlighting the contributions of Cavendish, Priestly, Lavoisier, and Black in identifying hydrogen, oxygen, and carbon dioxide respectively. Oxygen measurement relies on the paramagnetic property and can be precisely quantified.
  • Inspired air contains a lower partial pressure of oxygen compared to atmospheric air. Oxygen partial pressure drops from the atmosphere through the nose, lungs, capillaries, and mitochondria, where it is critical for energy production through combination with glucose. Hypoxia leads to reduced ATP production, causing listlessness and potential cardiac arrest.
  • The oxygen dissociation curve shows that saturation falls rapidly below 90%, meaning that clinical intervention should begin at 94%. The speaker describes the operation of electrodes used to measure pH, PO2, and PCO2 in blood gas analysis. She highlights that Hemoglobin carries limited amount of oxygen and cannot go above 100% saturation but dissolved O2 in plasma can improve.
  • Blood gas analysis helps diagnose and assess the severity of respiratory distress, differentiate between respiratory, cardiac, renal, and other system dysfunctions. It also helps guide therapy such as adjusting oxygen, CPAP/BiPAP, or mechanical ventilation in ICU patients. Blood gas analysis can be used to monitor the patient during and sleep studies.
  • Normal blood gas values are presented, emphasizing the difference between oxygen saturation (percentage of hemoglobin bound to oxygen) and oxygen content (total amount of oxygen in the blood). pH is balanced by the interaction of hydrogen and hydroxide ions in the body. Deviations in pH indicate either acidosis or alkalosis.
  • Acid-base analysis steps include comprehensive history, electrolytes, and ABG results. The goal is to identify the primary disorder, compensatory mechanisms, and appropriate anion gap. Respiratory disorders are compensated by renal adjustments, and metabolic disorders by respiratory adjustments, with maximum compensation limits for acute and chronic conditions.
  • Respiratory acidosis and alkalosis are compensated by renal adjustments in bicarbonate reabsorption. The speaker provided the formulas for respiratory acidoses acute and chronic to see how the Bicarb moves up or down to determine the degree of the compensation if any.
  • The speaker introduces metabolic acidosis and alkalosis, and how they cause corresponding changes to PCO2. She also recommends Binta’s formula for metabolic disorders as a tool. After diagnosing the type, one has to find out is there an expected compensation. She also recommends the anion gap measurement.
  • Anion gap calculation involves sodium, potassium, and magnesium. The difference between cations and anions indicates unmeasured anions. Normal urine anion gap indicates high urinary ammonia, while positive gap indicates low urinary ammonia, reflecting renal dysfunction.
  • A seven-step approach to blood gas interpretation is presented: assess pH, identify the culprit (PCO2 or bicarbonate), determine if it is respiratory or metabolic, assess compensation, calculate anion gap, consider clinical context, and identify if it is a single or mixed acid-base disorder.

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