Colon cancer is the third most common cancer globally and the second leading cause of cancer in the UAE and the UK. A significant portion of colon cancer cases are preventable through improved diet and increased physical activity, highlighting the direct influence of dietary choices on bowel health.
While the exact causes of cancer remain elusive, genetic predisposition and environmental factors, including diet, play crucial roles. While genetics are unchangeable, modifying environmental factors, especially diet, can significantly impact cancer risk.
Cancer development often involves inflammatory and oxidative pathways that disrupt normal cell multiplication, leading to genetic mutations and ultimately, cancer. Preventing or reducing cancer risk involves understanding factors that cause inflammation and oxidative stress.
Diet has a direct impact on colon cancer due to the direct contact of food with the digestive tract lining. While occasional dietary lapses aren't immediately harmful, consistent exposure to carcinogens increases risk. Studies primarily focus on associations between food types and cancer development due to ethical constraints preventing direct causal studies.
The adenoma-carcinoma sequence outlines the progression from normal lining to precancerous adenoma and then to cancer, a process that can take years. This extended timeframe allows for screening and intervention, like colonoscopies, to detect and address precancerous growths.
Prevention is vital due to the severity of advanced colon cancer and limitations in late-stage treatment. Early detection through screening colonoscopies is crucial. While advanced screening technologies exist, numerous barriers, like lack of symptoms, busy lifestyles, and cultural beliefs, hinder early detection rates.
Dairy products, especially low-fat options rich in calcium and vitamin D, have demonstrated anti-carcinogenic effects. Calcium supplements are also important for the immune system. High-fiber whole grains and cereals, good sources of magnesium, promote regular bowel movement and reduce stool contact with the intestinal lining.
Beans, pulses, lentils, and soybeans are rich in fiber, protein, and vitamin E, an antioxidant. Rainbow-colored fruits and vegetables are excellent sources of fiber, vitamin C, and anti-inflammatory agents. Fish, especially wild salmon, is rich in omega-3 fatty acids, known for their anti-cancer properties.
Red meat consumption should be moderate, while processed meats have been classified as carcinogenic to humans by the WHO. High-fat diets can contribute to colon cancer due to increased bile acid production and inflammation. Obesity is also associated with cancer risk, potentially due to inflammation, gut microbiome alterations, or poor dietary habits.
The presenter displayed examples of a balanced, plant-based meal. Suggestions included increasing physical activity, maintaining a healthy weight, consuming plenty of fruits and vegetables, reducing red and processed meat intake, avoiding excessive alcohol, and abstaining from smoking.
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