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Systemic Therapy for Advanced Hepatocellular Cancer
About the Speaker
Dr. Abdul Rahman Agha El Kinge
HOD Hematology Oncology, Fakeeh University Hospital, DXB
Upcoming Case Discussions
Treatment of Renal Disease in ANCA Vasculitis
The treatment of renal disease in ANCA-associated vasculitis (AAV) typically involves a combination of immunosuppressive therapies to control inflammation and prevent further kidney damage. First-line treatment often includes high-dose corticosteroids and cyclophosphamide or rituximab, both of which help to induce remission by targeting the underlying immune system dysfunction. In cases of kidney failure or rapidly progressive glomerulonephritis, plasmapheresis may be used to remove circulating autoantibodies. Once remission is achieved, maintenance therapy with lower doses of immunosuppressants, such as azathioprine or mycophenolate mofetil, is used to prevent relapses and preserve kidney function.
Clinician’s Approach to Multiple Fractures
A clinician's approach to multiple fractures involves a systematic assessment to prioritize life-threatening injuries and stabilize the patient. This typically includes evaluating the severity and location of fractures, considering any associated complications like hemorrhage or organ injury, and determining the best course for surgical or conservative management. Early intervention, pain management, and multidisciplinary coordination are key to optimizing recovery and preventing long-term disability.
Medical Management of Endometriosis
Medical management of endometriosis typically involves the use of hormonal therapies such as birth control pills, progestins, or GnRH agonists to reduce estrogen levels and suppress the growth of endometrial tissue. Pain management with NSAIDs, as well as targeted treatments like aromatase inhibitors or the use of intrauterine devices (IUDs), can help alleviate symptoms. In some cases, additional treatments like surgery may be considered for severe cases or when fertility is a concern.
Building Strong Interpersonal Relationships
A case discussion can highlight real-life situations where strong interpersonal relationships are essential, such as handling challenging patients or working effectively with colleagues. Sharing personal or professional experiences, or observations of successful interactions, can provide valuable insights. Emphasizing the key factors that contributed to building trust, mutual respect, and effective communication can help illustrate how strong relationships improve collaboration and patient care. This approach encourages participants to reflect on their own interactions and apply these strategies in their professional environments.
Ventilator Patient Asynchrony
Ventilator patient asynchrony occurs when there is a mismatch between the patient’s respiratory efforts and the ventilator’s delivered breaths. Common types include trigger asynchrony, flow asynchrony, and cycle asynchrony. Causes may include improper ventilator settings, altered respiratory mechanics, or patient conditions like agitation or airway obstruction.Diagnosis involves clinical observation and ventilator waveform analysis. Management focuses on optimizing ventilator settings, such as adjusting trigger sensitivity, inspiratory flow rates, or cycling thresholds. Sedation or neuromuscular blockade may be considered in severe cases. Regular monitoring and multidisciplinary collaboration are essential to ensure effective ventilation and improve patient outcomes.
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