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Mpox: Clinical Variations & Considerations

The Mpox virus (MPXV) is a double-stranded DNA virus that is zoonotic and causes Mpox, a disease that resembles smallpox but is less severe. The first incidence of MPXV was documented in 1970 in a 9-month-old boy in the Democratic Republic of the Congo. The virus was initially characterized in 1958. The three main signs of mpox are fever, lymphadenopathy, and rash. Rare are complications such encephalitis or widespread skin and mucous membrane lesions. As a result, Mpox death rates are comparatively low, with cases recorded after 2000 showing a range of 0 to 10%. The symptoms that were most commonly mentioned were fever, headache, cough, and sore or dry throat. Mpox lesions mostly appeared in the anal or genital regions.

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Dr. Venkat Ramesh

Consultant Infectious Disease, Apollo Hospitals, Hyderabad

Dr. Venkat Ramesh, Consultant Infectious Disease, Apollo Hospitals, Hyderabad

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The Mpox virus (MPXV) is a double-stranded DNA virus that is zoonotic and causes Mpox, a disease that resembles smallpox but is less severe. The first incidence of MPXV was documented in 1970 in a 9-month-old boy in the Democratic Republic of the Congo. The virus was initially characterized in 1958. The three main signs of mpox are fever, lymphadenopathy, and rash. Rare are complications such encephalitis or widespread skin and mucous membrane lesions. As a result, Mpox death rates are comparatively low, with cases recorded after 2000 showing a range of 0 to 10%. The symptoms that were most commonly mentioned were fever, headache, cough, and sore or dry throat. Mpox lesions mostly appeared in the anal or genital regions.