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Case based approach to Glomerular Disorders
A case-based approach to Glomerular Disorder involves a detailed patient history and clinical presentation to identify the underlying type of glomerulopathy. Such an approach often begins with the analysis of symptoms like edema, hematuria, and proteinuria, coupled with laboratory assessments including serum creatinine, electrolytes, and urine analysis. Renal biopsy plays a crucial role in diagnosing the specific type of glomerular disease, whether it's a primary disorder like Minimal Change Disease, Focal Segmental Glomerulosclerosis, or a systemic condition like Lupus Nephritis. The case discussion would also encompass treatment strategies tailored to the specific disorder, including corticosteroids, immunosuppressants, or supportive treatments like antihypertensives and dietary modifications. Regular monitoring for renal function and potential complications is also a critical part of management in these cases.
About the Speaker
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Dr. Varun Kumar Bandi
Associate Professor, Department of Nephrology, Dr. Pinnamaneni SIMS& RF, Vijayawada
Dr. Varun Kumar Bandi is a qualified Nephrologist with extensive educational and professional experience. He completed his MBBS at Vydehi Institute on Medical Sciences & Research Centre and pursued an MD in General Medicine at Jawaharlal Nehru Medical College. Later, he specialized in DM (Nephrology) at Sri Ramachandra Medical College. Dr. Bandi holds several certifications, including a FISN from the International Society of Nephrology. He has participated in various research and leadership programs, enhancing his expertise in the field. Currently, he is an Associate Professor and Head of the Department of Nephrology at Dr. Pinnamaneni Siddhartha Institute of Medical Sciences & Research Foundation.
Upcoming Case Discussions
Clinician’s Approach to Hypertensive Nephropathy
Many processes influence the management of chronic kidney disease (CKD) and lead to the development of hypertension in the disease. Increased sympathetic tone in patients with chronic kidney disease (CKD) is a result of afferent signals produced by functionally failing kidneys. The great majority of CKD patients suffer from hypertension, which can both cause and result from the disease. In people with CKD, controlling hypertension is crucial since it lowers the risk of CVD and slows the disease's course. There is no agreement on the ideal blood pressure (BP) targets provided by current guidelines. Consequently, when deciding how to care specific patients.
Anaphylaxis In Emergency Department
A dangerous systemic hypersensitivity reaction with a typically quick onset that can be fatal is anaphylaxis. Rapid onset of breathing, circulation,and/or airway issues are its defining characteristics. The most crucial treatment is intramuscular adrenaline, although many patients do not receive it even in medical facilities, despite recommendations to the contrary. The significance of positioning during the management of anaphylaxis and the necessity of avoiding activities that could postpone the timely and proper delivery of adrenaline. Antihistamines should only be used as a last resort when ABC characteristics have been successfully treated in order to lessen skin involvement.
Circulatory Shock In Trauma
The inability of the circulatory system to supply tissue oxygenation and organ perfusion necessary to meet cellular metabolic demands is known as shock. Although non-haemorrhagic shock, such as cardiogenic or neurogenic shock, can occur after trauma, hemorrhage is more frequently linked to trauma-related shock. Evidence gathered over the past ten years has shown that trauma patients suffer from acute traumatic coagulopathy (ATC), which is brought on by the actual process of injury. Damage control resuscitation (DCR), the current method for managing acute shock, was developed with this as a key component. Haemostatic resuscitation, which uses blood products as the main resuscitative fluid, permissive hypotension, and damage control surgery are the three main resuscitative techniques included in DCR.
Fertilization & Early Development
Fertilization occurs when a sperm cell merges with an egg cell, creating a zygote, which is the first stage of a new life. This process takes place in the fallopian tube. The zygote then undergoes rapid cell division, known as cleavage, forming a multi-cellular structure called a blastocyst. As the blastocyst moves toward the uterus, it continues to divide and develop. Approximately 5-7 days after fertilization, the blastocyst implants itself into the uterine lining, initiating pregnancy. Early development involves the formation of the foundational structures and systems that will shape the embryo.
Metabolic Syndrome and Heart Health
Metabolic syndrome is a cluster of conditions that increase the risk of heart disease, stroke, and type 2 diabetes. These conditions include high blood pressure, elevated blood sugar, excess body fat around the waist, and abnormal cholesterol or triglyceride levels. When these risk factors occur together, they amplify the risk of developing cardiovascular issues. Metabolic syndrome is closely linked to insulin resistance, where the body struggles to use insulin effectively. Lifestyle changes, such as adopting a healthy diet, regular exercise, and weight management, are crucial in managing the syndrome. Early intervention is essential to prevent the progression to heart disease and other complications.